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Colegio de Medicina Interna de México.

2025, Number 05

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Med Int Mex 2025; 41 (05)

Post-sepsis syndrome: strategies to prevent it. Descriptive review

Segura LV, González MKI, Morales RJD, Velázquez CA, Peña PCA, Cruz LJ

Language: Spanish
References: 37
Page: 291-301
PDF size: 236.97 Kb.


ABSTRACT

Background: Post-sepsis syndrome is an emerging condition that has attracted considerable interest among clinicians and researchers over the past two decades. It is characterized by a significantly increased risk of death and poor quality of life associated with a number of long-term sequelae that persist after sepsis.
Methodology: Descriptive (narrative) review of post-sepsis syndrome. PubMed and Google Scholar databases were searched for articles published in English between 2000 and 2020 using MeSH terms: Post-sepsis syndrome; Sepsis; Mortality that included epidemiologic data and suggestions for prevention of the syndrome.
Results: A total of 2,800 articles were found, of which 35 were selected for review and two others for additional epidemiologic information.
Conclusión: Mortality rates after surviving the initial episode of sepsis remain high, depending on its severity. The one-year mortality rate varies from 7 to 43%, and the five-year mortality rate can reach 80%, which is most often secondary to postsepsis syndrome because it increases the risk of readmission due to infection and the incidence of cognitive dysfunction, mental health problems, kidney damage, and cardiovascular disease.


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