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2025, Number 3

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Rev ADM 2025; 82 (3)

Adenomatoid odontogenic tumor. Presentation of 4 clinical cases and review of the literature.

Rodríguez AN, Albarrán GYF, Cruz LB, Montoya PLA, García CCR, Aldape BBC
Full text How to cite this article 10.35366/120436

DOI

DOI: 10.35366/120436
URL: https://dx.doi.org/10.35366/120436

Language: Spanish
References: 14
Page: 137-144
PDF size: 2822.43 Kb.


Key words:

adenomatoid odontogenic tumor, odontogenic neoplasm, adenomatoid odontogenic tumor.

ABSTRACT

Introduction: the adenomatoid odontogenic tumor (AOT) is a rare benign odontogenic tumor. AOT represents between 3 and 7% of all odontogenic neoplasms. It was first described by James W and Forbes JG in 1909, and later Philipsen HP in 1969 established the modern understanding of AOT, which is a encapsulated neoplasm composed of odontogenic epithelium with duct-like structures. Radiographically, it presents as a unilocular radiolucent area associated with an impacted tooth, most often the maxillary canine. Focal calcifications are present, and in most cases, they are discovered during the second decade of life. Some authors have considered AOT as a hamartoma. A peripheral variant has been described. Below, four cases of AOT are presented. Cases: the cases involve women aged 14, 15, 18, and 33 years. One case was diagnosed in the mandible as a periapical lesion, and three cases were associated with impacted maxillary canines. All cases are well-defined with mixed radiolucent and radiopaque areas. No root resorption was observed in the mandibular case. A slow growth pattern was reported in all cases. An excisional biopsy was performed in all four cases. Microscopically, all cases are encapsulated and composed of solid basaloid epithelium layers with duct-like spaces. Cystic and solid patterns with dystrophic calcifications were also observed. No recurrence was reported. Conclusion: although the mandibular case was located in an unusual position and had an atypical appearance, all cases demonstrated slow behavior. These cases confirm the benign nature of this tumor.


REFERENCES

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Rev ADM. 2025;82