2025, Number 4
Dual therapy of transarterial chemoembolization and atezolizumab plus bevacizumab for unresectable fibrolamellar hepatocellular carcinoma
González EIR, Cruz EM, Castro PA, Acosta PLE, Sánchez SS, Ruiz IGA, Quesnel SAJ
Language: Spanish
References: 5
Page: 394-396
PDF size: 270.51 Kb.
ABSTRACT
Introduction: fibrolamellar hepatocellular carcinoma (FLC) is a rare form of hepatocellular carcinoma affecting young patients. We present a case of unresectable FLC treated with transarterial chemoembolization and a combination of atezolizumab and bevacizumab. Case description: a 20-year-old woman with abdominal pain, nausea, and vomiting was diagnosed with well-differentiated FLC. A dual therapy regimen was implemented, achieving a 26.7% reduction in lesion size, maintained for 18.13 months. The overall survival was 22.23 months. Conclusion: FLC differs from conventional hepatocellular carcinoma and presents therapeutic challenges. The combination of chemoembolization and immunotherapy shows promising potential. This case adds valuable information about FLC in our country.REFERENCES