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NCT Neumología y Cirugía de Tórax

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Antes Revista del Instituto Nacional de Enfermedades Respiratorias

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2007, Number S1

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Neumol Cir Torax 2007; 66 (S1)

The clinical record and the laboratory

Orizaga FT, Rosas RMJR, Morales BJE
Full text How to cite this article

Language: Spanish
References: 15
Page: 23-28
PDF size: 300.72 Kb.


Key words:

Avian influenza, clinical features, outcome, laboratory findings, virologic diagnosis.

ABSTRACT

The avian influenza is caused by highly pathogenic virus A, transmitted from particularly farmer birds, pigs and poses a high risk for global public health. In humans the viral replication is prolonged, the virus could be detected in nasopharyngeal isolates for a median of 6.5 days, nasopharyngeal replication is less than in human influenza, and studies of low respiratory tract replication are needed. The initial symptoms in most patients have been high fever more than 38 °C, and influenza like illness with lower tract respiratory symptoms. Upper respiratory symptoms are present only sometimes. Also have been reported, diarrhea, vomiting, abdominal pain, pleuritic pain, and bleeding from the nose and gums have also been reported early in the course of illness. Commercial rapid antigen test are insensitive, and confirmatory diagnosis requires sophisticated laboratory support by an authorized World Health Authorized center.


REFERENCES

  1. World Health Organization. Recommended laboratory test to identify avian influenza A virus specimens from humans. WHO Geneva. June 2005 http://www.who.int/csr/disease/influenza/influenzanetwork/en/index.html).

  2. Wong SSY, Yuen KY. Avian Influenza Virus Infections in Humans CHEST 2006; 129: 156-168.

  3. Chotpitayasunondh T, Ungchusak K, Hanshaoworakul W, et al. Human disease from influenza A (H5N1), Thailand, 2004. Emerg Infect Dis 2005; 11: 201-9.

  4. John HB, Jeremy FD, Frederick GH. Avian Influenza A (H5N1) infection in Humans. The Writing committee of the World Health Organization (WHO) Consultation on Human Influenza A/H5. NEJM 2005; 353: 1374-85.

  5. Yuen KY, Chan PK, Peiris M, et al. Clinical features and rapid viral diagnosis of human disease associated with avian influenza A H5N1 virus. Lancet 1998; 351: 467-71.

  6. World Health Organization. WHO interim guidelines on clinical management of human infected by influenza A (H5N1). February 20, 2004. http://www.who.int/csr/disease/avian_influenza/guidelines/humanspecimens/en/index.html).

  7. World Health Organization. WHO interim guidelines Standard laboratory biosafety guidelines. http://www.who.int/csr/disease/avian_influenza/guidelines/handlingspecimens/en/index)

  8. World Health Organization. WHO interim guidelines. «national reference laboratory». http://www.who.int/csr/disease/influenza/centres/en/index.html).

  9. Recommended laboratory tests to identify avian influenza A virus in specimens from humans. WHO Geneva. June 2005

  10. http://www.who.int/csr/disease/avian_influenza/guidelines/referencelabs/en/index.htlm)

  11. http://www.who.int/csr/disease/avian influenza/guidelines/labtest/en/index.html) http://www.who.int/csr/disease/avian influenza/guidelines/definition2006 08 29/en/index.html)

  12. http://www.who.int/csr/disease/avian influenza/guidelines/Guidance sharing viruses specimens/en/index.html)

  13. WHO/CDS/EPR/ARO/2006.1.

  14. Secretaría de Salud. Plan Nacional de Preparación y Respuesta ante una Pandemia de Influenza. Secretaría de Salud-México 2006. www.salud.gob.mx

  15. Vigilancia de la influenza aviar. Circular de emergencia emitido por la SAGARPAhttp://www.cucba.udg.mx/influenza/panel.htm).




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Neumol Cir Torax. 2007;66