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Colegio de Medicina Interna de México.

2025, Number 07

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Med Int Mex 2025; 41 (07)

Clinical and neurophysiological profile of attention-deficit/hyperactivity disorder in women: An analysis using quantitative electroencephalography

Córdova PVH, Gutiérrez BD, Carapia MJ, Zabaneh CV

Language: Spanish
References: 44
Page: 386-401
PDF size: 536.70 Kb.


ABSTRACT

Objective: To analyze the clinical and neurophysiological profiles of women diagnosed with attention deficit hyperactivity disorder (ADHD) using quantitative electroencephalography (qEEG).
Materials and Methods: This descriptive study analyzed the clinical and neurophysiological profiles of female patients diagnosed with ADHD using qEEG. Three groups of variables were considered in the analysis: clinical (emotional dysregulation, anxiety, depression, and dysautonomia); performance (omissions, commissions, and response time); and neurophysiological (biomarkers obtained from qEEG). Spearman's rank correlation was used for statistical analysis to explore nonlinear relationships between ordinal variables, particularly between biomarkers and clinical and performance indicators.
Results: Forty-nine patients were studied, ranging in age from 4 to 64 years old (mean age 27 years), most of whom had not previously been diagnosed. A generalized pattern of alterations in attention performance was observed, with an average of 6.88 omissions, 2.88 commissions, and an average response time of 503 ms. These values reflect poor performance on sustained attention tasks, which is consistent with the characteristics of ADHD. The distribution of these results varied by age group. In girls under 12 years of age, the mean number of omissions was 7.3; in adolescents, it was 8.5, indicating greater difficulty in these subgroups.
Conclusions: The findings support the usefulness of qEEG as a complementary diagnostic tool for identifying specific ADHD phenotypes in females. There is a need for personalized assessment and intervention approaches.


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