2025, Number 2
<< Back Next >>
Rev Latin Infect Pediatr 2025; 38 (2)
Biofilms: an area of opportunity in the health sector
Zúñiga CIR, Caro LJ
Language: Spanish
References: 18
Page: 69-73
PDF size: 269.90 Kb.
ABSTRACT
Biofilms are defined as communities of microorganisms that grow in aggregates and surrounded by an extracellular matrix that they themselves produce. The extracellular matrix helps microbial cells evade the host's immune response; when biofilms form, they allow bacteria to grow in a protected environment, and thus, be able to survive hostile environments and then disperse to more favorable niches. More than 80% of all microbial infections are caused by biofilms, and they are responsible for 65% of health care associated infections, increasing hospital stays, care costs, and mortality in the diagnosis and treatment of the disease.
REFERENCES
Karatan E, Watnick P. Signals, regulatory networks, and materials that build and break bacterial biofilms. Microbiol Mol Biol Rev. 2009; 73 (2): 310-347.
O'Toole G, Kaplan H, Kolter R. Biofilm formation as microbial development. Ann Rev Microbiol. 2000; 54 (1): 49-79.
Burmolle M, Ren D, Bjarnsholt T, Sorensen S. Interactions in multispecies biofilms: do they actually matter? Trends Microbiol. 2014; 22 (2): 84-91.
Ortega S, Hernández E. Biopelículas microbianas y su impacto en áreas médicas: fisiopatología, diagnóstico y tratamiento. Bol Med Hosp Infant Mex. 2018; 75 (2): 79-88
Lasa I, del Pozo J, Penadés J, Leiva J. Biofilms bacterianos e infección. An Sist Sanit Navar. 2005; 28 (2): 163-175.
Wei Q, Ma L. Biofilm matrix and its regulation in Pseudomonas aeruginosa. Int J Mol Sci. 2013; 14 (10): 20983-21005.
Li Y, Tian X. Quorum sensing and bacterial social interactions in biofilms. Sensors. 2012; 12 (3): 2519-2538.
Heindl J, Wang Y, Heckel B, Mohari B, Feirer N, Fuqua C. Mechanisms and regulation of surface interactions and biofilm formation in Agrobacterium. Front Plant Sci. 2014; 5 (176): 1-21.
Jamal M, Ahmad W, Andleeb S, Jalil F, Imran M, Nawaz MA et al. Bacterial biofilm and associated infections. J Chin Med Assoc. 2018; 81 (1): 7-11.
Zambrano M, Suárez L. Biofilms bacterianos: sus implicaciones en salud y enfermedad. Univ Odontol. 2006; 25 (57): 19-25.
Lasa I. Biofilms bacterianos. Actualidad SEM. 2005; 37: 14-18.
Jakobsen T, Tolker T, Givskov M. Bacterial biofilm control by perturbation of bacterial signaling processes. Int J Mol Sci. 2017; 18 (9): 1970.
Rabin N, Zheng Y, Opoku C, Du Y, Bonsu E, Sintim HO. Biofilm formation mechanisms and targets for developing antibiofilm agents. Future Med Chem. 2015; 7 (4): 493-512.
Ma L, Conover M, Lu H, Parsek M, Bayles K, Wozniak DJ. Assembly and development of the Pseudomonas aeruginosa biofilm matrix. PLoS Pathogens. 2009; 5 (3): e1000354.
Yang L, Barken K, Skindersoe M, Christensen AB, Givskov M, Tolker-Nielsen T. Effects of iron on DNA release and biofilm development by Pseudomonas aeruginosa. Microbiology (Reading). 2007; 153 (5): 1318-1328.
Reducción de gérmenes en el agua. Minimizar la formación de biofilms. Aqua free Solución. Disponible en: https://www.aqua-free.com/es/revista/1
Early DM. The menace of biofilm and how we can tackle it. Water innovations. 2021.
Romero-González AT. Biofilm y resistencia antimicrobiana. Arch Méd Camagüey. 2020; 24 (4).