2022, Number 4
Usefulness of cardiac magnetic resonance imaging with parametric mapping in the diagnosis and prognosis of patients with cardiomyopathies
Language: Spanish
References: 42
Page: 320-331
PDF size: 667.95 Kb.
ABSTRACT
Introduction: Cardiomyopathies constitute a heterogeneous group of myocardial diseases with high morbidity and mortality. Cardiac magnetic resonance imaging (cMRI) plays an essential role in their diagnosis and prognosis.Objective: To describe the usefulness of cMRI by applying parametric maps in the diagnosis and prognosis of patients with cardiomyopathies.
Method: An observational, descriptive, cross-sectional study was conducted with 40 patients suffering from cardiomyopathies, treated at the Instituto de Cardiología y Cirugía Cardiovascular of Havana, Cuba, in 2018, who underwent cMRI and were followed for 24 months.
Results: Men (60%) and arterial hypertension (50%) were more frequent. cMRI con-firmed the initial diagnosis in 47% of cases. The ejection fraction was significantly lower in the deceased (p=0.039), who also presented higher end-diastolic and end-systolic volumes. Patients with decreased ventricular function presented higher ex-tracellular volumes (mean of 38.9 ms), and higher mortality at 24 months of follow-up. The native T1 and extracellular volume values were significantly higher in the deceased with mean of 1134.4 and 41.4 ms respectively.
Conclusions: cMRI complements the noninvasive diagnosis and prognosis of cardi-omyopathies by confirming, adding or refuting diagnoses through assessment of ventricular function and tissue characterization, where ejection fraction and extra-cellular volume are the most important prognostic variables.
REFERENCES
Maron BJ, Towbin JA, Thiene G, Antzelevitch C, Corrado D, Arnett D, et al. Contemporary defini-tions and classification of the cardiomyopathies: An American Heart Association Scientific State-ment from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Func-tional Genomics and Translational Biology Inter-disciplinary Working Groups; and Council on Epi-demiology and Prevention. Circulation. 2006; 113(14):1807-16. [DOI]
Messroghli DR, Moon JC, Ferreira VM, Grosse-Wort-mann L, He T, Kellman P, et al. Clinical recommen-dations for cardiovascular magnetic resonance map- ping of T1, T2, T2* and extracellular volume: A con-sensus statement by the Society for Cardiovascular Magnetic Resonance (SCMR) endorsed by the Euro-pean Association for Cardiovascular Imaging (EACVI). J Cardiovasc Magn Reson [Internet]. 2017 [citado 21 Oct 2021];19(1):75. Disponible en: https://doi.org/10.1186/s12968-017-0389-8
Schulz-Menger J, Bluemke DA, Bremerich J, Flamm SD, Fogel MA, Friedrich MG, et al. Standard-ized image interpretation and post-processing in cardiovascular magnetic resonance - 2020 update: Society for Cardiovascular Magnetic Resonance (SCMR): Board of Trustees Task Force on Stand-ardized Post-Processing. J Cardiovasc Magn Reson [Internet]. 2020 [citado 27 Oct 2021];22(1):19. Dis-ponible en: https://doi.org/10.1186/s12968-020-00610-6
Cerqueira MD, Weissman NJ, Dilsizian V, Jacobs AK, Kaul S, Laskey WK, et al. Standardized myo-cardial segmentation and nomenclature for tomo-graphic imaging of the heart. A statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association. Circulation. 2002; 105(4):539-42. [DOI]
Petersen SE, Aung N, Sanghvi MM, Zemrak F, Fung K, Paiva JM, et al. Reference ranges for cardiac structure and function using cardiovascular mag-netic resonance (CMR) in Caucasians from the UK Biobank population cohort. J Cardiovasc Magn Re-son [Internet]. 2017 [citado 28 Oct 2021];19(1):18. Disponible en: https://doi.org/10.1186/s12968-017-0327-9
Pérez Barreda A, Marcos Gutiérrez Y, Peix Gonzá-lez A, Bencomo Rodríguez L, Martínez González A, Padrón García KM, et al. Estado actual de la reso-nancia magnética cardíaca en Cuba. Perspectivas futuras. Rev Cuban Cardiol [Internet]. 2019 [citado 31 Oct 2021];25(1). Disponible en: https://revcar-diologia.sld.cu/index.php/revcardiologia/arti-cle/view/834/pdf
Kwong RY, Petersen SE, Schulz-Menger J, Arai AE, Bingham SE, Chen Y, et al. The global cardiovascu-lar magnetic resonance registry (GCMR) of the so-ciety for cardiovascular magnetic resonance (SCMR): its goals, rationale, data infrastructure, and current developments. J Cardiovasc Magn Re-son [Internet]. 2017 [citado 31 Oct 2021];19(1):23. Disponible en: https://doi.org/10.1186/s12968-016-0321-7
Bruder O, Wagner A, Lombardi M, Schwitter J, van Rossum A, Pilz G, et al. European Cardiovascular Magnetic Resonance (EuroCMR) registry – Multi national results from 57 centers in 15 countries. J Cardiovasc Magn Reson [Internet]. 2013 [citado 31 Oct 2021];15(1):9. Disponible en: https://doi.org/10.1186/1532-429x-15-9
Nagata Y, Wu VC, Kado Y, Otani K, Lin FC, Otsuji Y, Negishi K, Takeuchi M. Prognostic Value of Right Ventricular Ejection Fraction Assessed by Trans-thoracic 3D Echocardiography. Circ Cardiovasc Imaging [Internet]. 2017 [citado 1 Nov 2021];10(2): e005384. Disponible en: https://doi.org/10.1161/cir-cimaging.116.005384
Minegishi S, Kato S, Takase-Minegishi K, Horita N, Azushima K, Wakui H, et al. Native T1 time and ex-tracellular volume fraction in differentiation of nor-mal myocardium from non-ischemic dilated and hypertrophic cardiomyopathy myocardium: A sys-tematic review and meta-analysis. Int J Cardiol Heart Vasc [Internet]. 2019 [citado 2 Nov 2021]; 25:100422. Disponible en: https://doi.org/10.1016/j.ijcha.2019.100422
Yang EY, Ghosn MG, Khan MA, Gramze NL, Brun-ner G, Nabi F, Nambi V, Nagueh SF, Nguyen DT, Graviss EA, Schelbert EB, Ballantyne CM, Zoghbi WA, Shah DJ. Myocardial Extracellular Volume Fraction Adds Prognostic Information Beyond My-ocardial Replacement Fibrosis. Circ Cardiovasc Imaging [Internet]. 2019 [citado 4 Nov 2021];12(12): e009535. Disponible en: https://doi.org/10.1161/cir-cimaging.119.009535
Yang EY, Khan MA, Graviss EA, Nguyen DT, Bhim-araj A, Nambi V, et al. Relationship of extracellular volume assessed on cardiac magnetic resonance and serum cardiac troponins and natriuretic pep-tides with heart failure outcomes. Sci Rep [Inter-net]. 2019 [citado 4 Nov 2021];9(1):20168. Disponi-ble en: https://doi.org/10.1038/s41598-019-56213-4