medigraphic.com
SPANISH

CorSalud (Revista de Enfermedades Cardiovasculares)

ISSN 2078-7170 (Electronic)
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2022, Number 4

<< Back Next >>

CorSalud 2022; 14 (4)

Frank´s sign or diagonal earlobe crease in a patient with acute myocardial infarction

Rodríguez LLA, Rodríguez ME, González AJA, Lhasa P, Apaza NN, Peñate HCM
Full text How to cite this article

Language: Spanish
References: 14
Page: 400-404
PDF size: 746.80 Kb.


Key words:

Constrictive pericarditis, Multimodality imaging, Echocardiography, Cardiac CT, Magnetic resonance imaging, Pericardiectomy.

ABSTRACT

Atherosclerosis is a chronic, inflammatory, immune disease of the arterial wall, in whose genesis genetic factors and lifestyle are involved. The early detection of its symptoms and clinical signs in patients at cardiovascular risk is of vital importance for the timely diagnosis of cardiovascular diseases. We present the case of a 72-year-old male with a history of type 2 diabetes mellitus, hypercholesterolemia, chronic high blood pressure and smoking —all important cardiovascular risk factors— who came to the emergency department with chest pain and was diagnosed with ST-segment elevation acute myocardial infarction, from atherosclerotic cause. The physical examination revealed Frank's sign or diagonal earlobe crease, which is a diagonal crease in the earlobe. This extracardiac cutaneous sign is a marker of is-chemic heart disease due to generalized obstructive atherosclerosis, which is asso-ciated with an increased likelihood of coronary artery disease or stroke.


REFERENCES

  1. Thygesen K, Alpert JS, Jaffe AS, Chait- man BR, Bax JJ, Morrow DA, et al. Consenso ESC 2018 sobre la cuarta definición universal del infarto de miocardio. Rev Esp Cardiol. 2019; 72(1):72.e1-e27. [DOI]

  2. White J, Swerdlow DI, Preiss D, Fair-hurst-Hunter Z, Keating BJ, Assel-bergs FW, et al. Association of lipid fractions with risks for coronary artery disease and diabetes. JAMA Cardiol. 2016;1(6):692-9. [DOI]

  3. Stone NJ, Robinson JG, Lichtenstein AH, Bairey Merz CN, Blum CB, Eckel RH, et al. 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardi-ology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2014;63(25 Pt B):2889-934. [DOI]

  4. Frank ST. Aural sign of coronary-artery disease. N Engl J Med. 1973;289(6):327-8. [DOI]

  5. Sanchis J, Soler M, Núñez J, Ruiz V, Bonanad C, Formiga F, et al. Comorbidity assessment for mor-tality risk stratification in elderly patients with acute coronary syndrome. Eur J Intern Med. 2019; 62:48-53. [DOI]

  6. Nazzal S, Hijazi B, Khalila L, Blum A. Diagonal Ear-lobe Crease (Frank's Sign): A Predictor of Cerebral Vascular Events. Am J Med. 2017;130(11): 1324.e1-e5. [DOI]

  7. Davis TM, Balme M, Jackson D, Stuccio G, Bruce DG. The diagonal ear lobe crease (Frank's sign) is not associated with coronary artery disease or re-tinopathy in type 2 diabetes: the Fremantle Diabe-tes Study. Aust N Z J Med. 2000;30(5):573-7. [DOI]

  8. Brotons C, Moral I, Fernández D, Puig M, Calvo Bonacho E, Martínez Muñoz P, et al. Estimación del riesgo cardiovascular de por vida (IBERLIFE-RISK): una herramienta nueva en prevención pri-maria de las enfermedades cardiovasculares. Rev Esp Cardiol. 2019;72(7):562-8. [DOI]

  9. Carillo-Esper R, Carrillo-Córdova JR, Carrillo-Cór-dova LD. Signo del lóbulo hendido, ¿curiosidad clínica o marcador de cardiopatía isquémica? Gac Med Mex. 2010;146(3):225-7. [Enlace]

  10. Cheng TO. More research needed on the associa-tion between diagonal earlobe crease and coro-nary artery disease. Arch Intern Med. 2000; 160(15):2396-7. [DOI]

  11. Christoffersen M, Frikke-Schmidt R, Schnohr P, Jensen GB, Nordestgaard BG, Tybjærg-Hansen A. Visible age-related signs and risk of ischemic heart disease in the general population: a pro-spective cohort study. Circulation. 2014;129(9): 990-8. [DOI]

  12. Vázquez-Oliva G, Zamora A, Ramos R, Marti R, Subirana I, Grau M, et al. Tasas de incidencia y mortalidad, y letalidad poblacional a 28 días del infarto agudo de miocardio en adultos mayores. Estudio REGICOR. Rev Esp Cardiol. 2018;71(9): 718-25. [DOI]

  13. Wu XL, Yang DY, Zhao YS, Chai WH, Jin ML. Diag-onal earlobe crease and coronary artery disease in a Chinese population. BMC Cardiovasc Disord [Internet]. 2014 [citado 14 Ene 2022];14:43. Dispo-nible en: https://doi.org/10.1186/1471-2261-14-43

  14. Friedlander AH, Scully C. Diagonal ear lobe crease and atherosclerosis: A review of the medi-cal literature and oral and maxillofacial implica-tions. J Oral Maxillofac Surg. 2010;68(12):3043-50. [DOI]




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

CorSalud. 2022;14