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2025, Number 08

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Med Int Mex 2025; 41 (08)

Microorganisms associated with vascular access infections in hemodialysis and their antimicrobial susceptibility

Díaz JJ, Miranda AA, Ramos NJC, Serrano OR, Lugo MJA
Full text How to cite this article

Language: Spanish
References: 25
Page: 457-464
PDF size: 198.65 Kb.


Key words:

Vascular access, Hemodialysis, Blood cultures, Anti-bacterial agents, Enterobacter cloacae, Ciprofloxacin, Staphylococcus aureus, Staphylococcus epidermidis, Prevalence.

ABSTRACT

Objetive: To evaluate the prevalence of infectious agents and antimicrobial susceptibility in patients with vascular access-related infections.
Materials and Methods: This was a clinical, epidemiological, observational, retrospective, and cross-sectional study. We reviewed the clinical records and laboratory data of patients who underwent hemodialysis at the IMSS Hospital de Especialidades 2 in Ciudad Obregón, Sonora, between September 1, 2021, and August 31, 2024. Positive blood cultures and their sensitivity profiles were analyzed using Pearson chi-square test.
Results: Of the 225 positive blood cultures, 52% corresponded to Gram-positive microorganisms, and 48% corresponded to Gram-negative microorganisms. The most frequent microorganisms were Staphylococcus epidermidis (31.1%), Enterobacter cloacae (15.6%), and Staphylococcus aureus (9.3%). Gentamicin (55.1%) and ciprofloxacin (49.3%) were the most effective antibiotics. The non-tunneled venous catheter was the most common access route (71.4%). In the inferential analysis, no association was found between the type of venous access and the type of infectious agent.
Conclusion: There was no significant association between the type of vascular access and the infectious agent. The main microorganisms causing infections were S. epidermidis and E. cloacae, and antimicrobial sensitivity testing showed good results with gentamicin and ciprofloxacin.


REFERENCES

  1. Levin A, Stevens PE, Bilous RW, Coresh J, et al. Kidney disease:Improving global outcomes (KDIGO) CKD work group. KDIGO 2012 clinical practice guideline for the evaluation and managementof chronic kidney disease. Vol. 3, Kidney InternationalSupplements. 2013.https://doi.org/10.1038/kisup.2012.73

  2. Lorenzo V, López J. Principios físicos en hemodiálisis. ContribNephrol 2017; 191 (4).

  3. Mohajerani F, Clark WR, Ronco C, Narsimhan V. MassTransport in High-Flux Hemodialysis Application of EngineeringPrinciples to Clinical Prescription. CJASN 2022; 17(5). https://doi.org/10.2215/CJN.09410721

  4. Martínez-Cercós R, Foraster A, Cebollada J, Álvarez-LipeR, et al. Consensos accesos vasculares para hemodiálisis.Dialisis y Trasplante 2008; 29 (4).

  5. Ravani P, Palmer SC, Oliver MJ, Quinn RR, et al. Associationsbetween hemodialysis access type and clinical outcomes:A systematic review. CJASN 2013;24(3). https://doi.org/10.1681/ASN.2012070643

  6. Sequeira A, Naljayan M, Vachharajani TJ. Vascular AccessGuidelines: Summary, Rationale, and Controversies. TechVasc Interv Radiol 2017; 20 (1). https://doi.org/10.1053/j.tvir.2016.11.001

  7. Quittnat Pelletier F, Joarder M, Poutanen SM, Lok CE. Evaluatingapproaches for the diagnosis of hemodialysis catheter–related bloodstream infections. CJASN 2016;11(5).

  8. Safdar N, Fine JP, Maki DG. Meta-analysis: Methods fordiagnosing intravascular device-related bloodstream infection.Vol. 142, Annals of Internal Medicine. 2005.

  9. Fernández Cantón S. El IMSS en cifras: la mortalidad dela población derechohabiente, 2003. Revista Médica delIMSS. 2004;42(4).

  10. Treviño A. Insuficiencia renal crónica: enfermedad emergente,catastrófica y por ello prioritaria. Academia Mexicanade Cirugía. 2004;72(1).

  11. INEGI. Vol. 2020, Censo de Población y Vivienda 2020.2020. INEGI. Censo de Población y Vivienda 2020.

  12. Méndez-Durán A, Méndez-Bueno JF, Tapia-Yáñez T, MontesAM, et al. Epidemiología de la insuficiencia renal crónicaen México. In: Dialisis y Trasplante 2010; 7-11. https://doi.org/10.1016/S1886-2845(10)70004-7

  13. SEGOB. Boletín Infecciones Asociadas a la Atención de laSalud (IAAS) Red Hospitalaria de Vigilancia Epidemiológica(RHOVE) 2022. Secretaría de Salud. 2022.

  14. Patel PR, Kallen AJ, Arduino MJ. Epidemiology, surveillance,and prevention of bloodstream infections in hemodialysispatients. American Journal of Kidney Diseases 2010; 56 (3).https://doi.org/10.1053/j.ajkd.2010.02.352

  15. Ravani P, Quinn R, Oliver M, Robinson B, et al. Examiningthe association between hemodialysis access type andmortality: The role of access complications. CJASN 2017;12 (6). https://doi.org/10.2215/CJN.12181116

  16. Lok CE, Foley R. Vascular access morbidity and mortality:Trends of the last decade. CJASN 2013; 8 (7). https://doi.org/10.2215/CJN.01690213

  17. Lata C, Girard L, Parkins M, James MT. Catheter-relatedbloodstream infection in end-stage kidney disease: ACanadian narrative review. Canadian Journal of KidneyHealth and Disease 2016; 3. https://doi.org/10.1186/s40697-016-0115-8

  18. Miller LM, Clark E, Dipchand C, Hiremath S, et al.Hemodialysis tunneled catheter-related infections.Can J Kidney Health Dis 2016; 3 (1). https://doi.org/10.1177/2054358116669130

  19. Lok CE, Mokrzycki MH. Prevention and management ofcatheter-related infection in hemodialysis patients. KidneyInternational 2011; 79: 587-98. https://doi.org/10.1038/ki.2010.471

  20. Mokrzycki MH, Zhang M, Cohen H, Golestaneh L, et al.Tunnelled haemodialysis catheter bacteraemia: Risk factorsfor bacteraemia recurrence, infectious complicationsand mortality. Nephrology Dialysis Transplantation 2006;

  21. 21 (4). https://doi.org/10.1093/ndt/gfi10421. Harish A, Allon M. Arteriovenous graft infection: A comparisonof thigh and upper extremity grafts. CJASN 2011;6 (7). https://doi.org/10.2215/CJN.00490111

  22. Sychev D, Maya ID, Allon M. Clinical management ofdialysis catheter-related bacteremia with concurrentexit-site infection. Semin Dial 2011; 24 (2). https://doi.org/10.1111/j.1525-139X.2011.00869.x

  23. Murray EC, Marek A, Thomson PC, Coia JE. Gram-negativebacteraemia in haemodialysis. Nephrology Dialysis Transplantation2015; 30 (7). https://doi.org/10.1093/ndt/gfv205

  24. Tordoir J, Canaud B, Haage P, Konner K, et al. EBPG onvascular access. Vol. 22, Nephrology Dialysis Transplantation,2007.

  25. Guo H, Zhang L, He H, Wang L. Risk factors for catheterassociatedbloodstream infection in hemodialysis patients:A meta-analysis. PLoS One 2024; 19. https://doi.org/10.1371/journal.pone.0299715




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Med Int Mex. 2025;41