2025, Number 8
Impact of the age of the recipient on the pregnancy rate in egg donation cycles
González GEL, Robellada ZCM, Carballo ME, Kably AA
Language: Spanish
References: 9
Page: 295-299
PDF size: 186.18 Kb.
ABSTRACT
Objective: To determine whether a woman's age affects the pregnancy rate in oocyte recipients.Methods and Materials: This retrospective, observational, descriptive study was conducted on patients who underwent in vitro fertilization and egg donation cycles at the Dr. Alberto Kably Mexican Fertility Center between 2005 and 2022. A p-value of less than 0.05 was considered statistically significant, and statistical analysis was performed using SPSS software.
Results: A total of 743 patients were studied and divided into five groups based on age: under 30, 31 to 35, 36 to 40, 41 to 45, and over 45 years old. The largest group was 40 to 44 years old (42.8%). The pregnancy rate was higher in the under-30 group than in those over 45 (p = 0.02). The highest miscarriage rate was recorded in patients over 45 years of age, with a more pronounced trend compared to patients under 30 and aged 40 to 44 (p = 0.001). Regarding endometrial thickness, a decrease in the pregnancy rate was observed when embryo transfers were performed with an endometrial thickness of 6 mm or less or 15 mm or more before progesterone administration.
Conclusion: These results are consistent with previous studies that reported a significant difference in pregnancy rates related to the age of oocyte recipients.
REFERENCES
Yeh JS, Steward RG, Dude AM, Shah AA, et al. Pregnancyoutcomes decline in recipients over age 44: An analysis of27,959 fresh donor oocyte in vitro fertilization cycles fromthe Society for Assisted Reproductive Technology. FertilSteril 2014; 101 (5): 1331-36. https://doi.org/10.1016/j.fertnstert.2014.01.056