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ISSN 1405-0625 (Print)

2025, Number 3

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Cir Plast 2025; 35 (3)

Safety and efficacy of autologous facial fat grafting in rejuvenation

Sánchez-García XA, Sánchez-Knupflemacher D

Language: Spanish
References: 10
Page: 134-139
PDF size: 364.66 Kb.


ABSTRACT

Autologous facial fat transfer has gained popularity as a rejuvenation technique for its ability to restore volume and improve skin quality naturally. However, variability persists in the literature regarding graft duration, complication rate, and degree of patient satisfaction. The objective of this work was to evaluate the safety and efficacy of autologous facial fat transfer in rejuvenation through a systematic review focused on volumetric retention, adverse events, and reported satisfaction levels. A systematic review was carried out in PubMed, Scopus, and Web of Science, covering the period from January 2015 to July 2024. Clinical studies in humans reporting functional or aesthetic results after facial lipoinjection were taken into account. Methodological quality was assessed through validated tools and the PRISMA 2020 statement was used to guide the process. Ten studies comprising a total of 1,245 patients were included. Volumetric retention ranged between 50% and 75% at 6-12 months. Complications were infrequent, the most common being partial resorption and contour irregularities. Patient satisfaction levels exceeded 90% in most studies. We concluded that autologous facial fat transfer is a safe and effective technique in facial rejuvenation, with high volume retention, few complications, and high patient satisfaction.


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