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2023, Number 2

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Gaceta Médica Espirituana 2023; 25 (2)

Clinical-epidemiologic characteristics of patients with non-alcoholic fatty liver disease: Case series

Nápoles VMB, Amaró GMA, Abreu CL, Alvarez BCR, Carrazana RK, Pereira BAL

Language: Spanish
References: 23
Page: 1-15
PDF size: 312.85 Kb.


ABSTRACT

Background: Nonalcoholic fatty liver disease is a resulting from fat accumulation in the absence of significant alcohol consumption. Most patients have a common epidemiologic link associated with metabolic risk factors.
Objective: To describe the clinical and epidemiologic characteristics of patients with nonalcoholic fatty liver disease.
Methodology: A descriptive study of a series of cases was carried out in the Gastroenterology consultation of the "Camilo Cienfuegos" Provincial General Hospital of Sancti Spíritus, during the period from May 6, 2019 through May 6, 2020. A total of 1167 patients belonging to the province of Sancti Spiritus were included in the study; 346 patients were diagnosed with hepatic steatosis by means of ultrasound; the sample consisted of 114 patients who fulfilled the inclusion criteria.
Results: Most patients with the disease were symptomatic, men, and had comorbidities including hypertension and obesity, the body mass index and the waist-to-hip ratio of the abdomen were increased in women., the blood chemistry changes were cholesterol and triacylglycerides.
Conclusions: It predominated in the male sex and comorbidity with HBP and obesity and dyslipidemia, in addition to inadequate dietary habits and sedentary lifestyle; in women, the anthropometric measurements were high.


REFERENCES

  1. Vera Anchundia JE. Transaminasas hepáticas como predictor de diagnóstico temprano de esteatosis enusuarios entre 5 y 14 años con sobrepeso y obesidad que acuden al servicio de pediatría del Hospital San Vicentede Paúl de la ciudad de Ibarra durante febrero a junio 2017. [Tesis previa a la obtención del título de Especialistaen Pediatría Internet]. Quito: Pontificia Universidad Católica del Ecuador; 2017. [citado 25 Dic 2022]. Disponibleen:http://repositorio.puce.edu.ec/bitstream/handle/22000/13739/TESIS%20ESTEATOSIS%20HEPATICAS.pdf?sequence=1&isAllowed=y

  2. Méndez-Sánchez N, Arrese M, Gadano A, Oliveira CP, Fassio E, Arab JP. Declaración de posición de laAsociación Latinoamericana para el Estudio del Hígado (ALEH) sobre la redefinición de la enfermedad del hígadograso. Lancet Gastroenterol Hepatol [Internet]. 2021 [citado 25 Dic 2022];6(1):65-72. Disponible en:https://smiba.org.ar/curso_medico_especialista/lecturas_2022/Declaraci%C3%B3n%20de%20posici%C3%B3n%20de%20la%20Asociaci%C3%B3n%20Latinoamericana%20para%20el%20Estudio%20del%20H%C3%ADgado%20%28ALEH%29%20sobre%20la%20redefinici%C3%B3n%20de%20la%20enfermedad%20del%20h%C3%ADgado%20graso.pdf

  3. Younossi Z, Tacke F, Arrese M, Chander Sharma B, Mostafa I, Bugianesi E, et al. Global perspectives onnonalcoholic fatty liver disease and nonalcoholic steatohepatitis. Hepatology [Internet]. 2019 [cited 2022 Dec25];69(6):2672-82. Available from:https://journals.lww.com/hep/Fulltext/2019/06000/Global_Perspectives_on_Nonalcoholic_Fatty_Liver.30.aspx

  4. Younossi Z, Anstee QM, Marietti M, Hardy T, Henry L, Eslam M, et al. Global burden of NAFLD and NASH:trends, predictions, risk factors and prevention. Gastroenterology & Hepatology [Internet]. 1 de enero de 2018[cited 2022 Dec 25];15(1):11-20. Available from: https://www.nature.com/articles/nrgastro.2017.109

  5. Castellanos-Fernández MI, Crespo-Ramírez E, del Valle-Díaz S, Barreto-Suárez E, Díaz-Elías JO, Santaló-Rodríguez L, et al. Non-Alcoholic Fatty Liver Disease in Cuba. Medicc Review [Internet]. 2021 [cited 2022 Dec25];23(1):64-71. Available from: https://www.medigraphic.com/pdfs/medicreview/mrw-2021/mrw211m.pdf

  6. Chalasani N, Younossi Z, Lavine JE, Charlton M, Cusi K, Rinella M, et al. The diagnosis and management ofnonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases.Hepatology [Internet]. 2018 [cited 2022 Dec 25];67(1):328-357. Available from:https://journals.lww.com/hep/Fulltext/2018/01000/The_diagnosis_and_management_of_nonalcoholic_fatty.31.aspx

  7. Organización Mundial de la Salud. Directrices de la OMS Sobre Actividad Física y ComportamientosSedentarios. [Internet]. Ginebra: OMS; 2021. [citado 25 Dic 2022]. Disponible en:https://apps.who.int/iris/bitstream/handle/10665/349729/9789240032194-spa.pdf?sequence=1&isAllowed=y

  8. Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive Summaryof the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation,and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMÁ [Internet]. 2001 [cited 2022Dec 25];285(19):2486-97. Available from: https://pubmed.ncbi.nlm.nih.gov/11368702/

  9. Sahuquillo Martínez A, Ramírez Manent JI, Torres Moreno MP, Solera Albero J, Tárraga López PJ. Laecografía, técnica diagnóstica en esteatosis hepática no alcohólica. JONNPR [Internet]. 2020 [citado 23 Dic 2022];5(4):392-427. Disponible en: https://scielo.isciii.es/pdf/jonnpr/v5n4/2529-850X-jonnpr-5-04-392.pdf

  10. Castro Soli L, Silva G. Hígado graso no Alcohólico. Rev Méd Clín Condes [Internet]. 2015 [citado 23 Dic2022];26(5):600-12. Disponible en: https://www.elsevier.es/es-revista-revista-medica-clinica-las-condes-202-pdf-S071686401500125X

  11. Younossi ZM. Non-alcoholic fatty liver disease–a global public health perspective. J Hepatol [Internet]. 2019[cited 2022 Dec 25];70(3):531-44. Available from: https://www.journal-of-hepatology.eu/article/S0168-8278(18)32517-0/pdf

  12. Brea A, Puzo J. Non-alcoholic fatty liver disease and cardiovascular risk. Int J Cardiol [Internet]. 2013 [cited2022 Dec 25];167(4):1109-17. Available from: https://sci-hub.mksa.top/10.1016/j.ijcard.2012.09.085

  13. Fung J, Lee CK, Chan M, Seto WK, Lai CL, Yuen MF, et al. High prevalence of non-alcoholic fatty liver diseasein the Chinese: results from the Hong Kong liver health census. Liver Int [Internet]. 2015 [cited 2022 Dec23];35(2):542-9. Available from: https://sci-hub.mksa.top/https://doi.org/10.1111/liv.12619

  14. Arab JP, Dirchwolf M, Álvares-da-Silva MR, Barrera F, Benítez C, Castellanos-Fernandez M, et all. LatinAmerican Association for the study of the liver (ALEH) practice guidance for the diagnosis and treatment of nonalcoholicfatty liver disease. Ann Hepatol [Internet]. 2020 [cited 2022 Dec 23];19(6):674-90. Available from:https://www.sciencedirect.com/science/article/pii/S1665268120301770

  15. Michel Mendoza NM, et al. Aspectos nutricionales y dietéticos en pacientes con hepatopatía grasa noalcohólica en un centro de atención terciaria. Arch Cubanos Gastroenterol [Internet]. 2021 [citado 23 Dic2022];1(3). Disponible en: https://revgastro.sld.cu/index.php/gast/article/view/42/145

  16. Ramos-López O, Román S, Ojeda-Granados C, Sepúlveda-Villegas M, Martínez-López E, Torres-Valadez R,et al. Patrón de ingesta alimentaria y actividad física en pacientes hepatópatas en el Occidente de México. RevEndocrinol Nutr [Internet]. 2013 [citado 23 Dic 2022];21(1):7-15. Disponible en:https://www.medigraphic.com/pdfs/endoc/er-2013/er131b.pdf

  17. Colectivo de autores. III Encuesta Nacional de factores de riesgo y actividades preventivas de Enfermedadesno transmisibles. Cuba 2010-2011 [Internet]. La Habana: Editorial Ciencias Médicas; 2015. [citado 23 Dic 2022].Disponible en: http://www.bvs.sld.cu/libros/encuesta_nacional_riesgo/encuesta_completo.pdf

  18. Lambis AL, Solana TJB, Gastelbondo PB, Romero SD, Garrido CD, Puello RW, et al. Factores de riesgoasociados a hígado graso de origen no alcohólico en una población del Caribe Colombiano. Rev Col Gastroenterol[Internet]. 2016 [citado 25 Dic 2022];31(2):89-95. Disponible en:http://www.scielo.org.co/pdf/rcg/v31n2/v31n2a01.pdf

  19. Zhao YC, Zhao GJ, Chen Z, She ZG, Cai J, Li H. Nonalcoholic fatty liver disease: an emerging driver ofhypertension. Hypertension [Internet]. 2020 [cited 2022 Dec 25];75(2):275-84. Available from:https://www.ahajournals.org/doi/epub/10.1161/HYPERTENSIONAHA.119.13419

  20. Sheka AC, Adeyi O, Thompson J, Hameed B, Crawford PA, Ikramuddin S, et al. Nonalcoholic steatohepatitis:a review. Jama [Internet]. 2020 [cited 2022 Dec 25];323(12):1175-83. Available from:https://jamanetwork.com/journals/jama/article-abstract/2763297

  21. Graffina M, Catoira N, Soutelo J, Azpelicueta A, Berg G, Perel C, et al. Diagnóstico de esteatosis hepática pormétodos clínicos, bioquímicos y por imágenes. Rev Argentina Endocrinol Metabol [Internet]. 2017 [citado 23 Dic2022];541(1):37-46. Disponible en: https://www.elsevier.es/es-revista-revista-argentina-endocrinologiametabolismo-185-pdf-S0326461016300651

  22. 22.Diaz-Elías J, Santaló-Rodríguez L, Fernández-Sotolongo J, González-Hernández O. Evaluación de losfactores de riesgo en el hígado graso no alcohólico. Archivos del Hospital Universitario "General Calixto García"[Internet]. 2021 [citado 5 Abr 2022];9(1):[aprox. 9 p.]. Disponible en:http://revcalixto.sld.cu/index.php/ahcg/article/view/633

  23. Batanero-Hernán MC, Escalera Izquierdo B, Fresno Contreras MJ, Rodríguez-Chamorro MA. Principalesenfermedades según el grupo sanguíneo en población mayor de 60 años en provincia de Cuenca (España). RevColomb Cienc Quím Farm [Internet]. 2020 [citado 23 Dic 2022];49(3):740-58. Disponible en:http://www.scielo.org.co/pdf/rccqf/v49n3/1909-6356-rccqf-49-03-740.pdf




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