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Revista Latinoamericana de Infectología Pediátrica

ISSN 2683-1678 (Print)
Órgano Oficial de la Sociedad
Latinoamericana de lnfectología Pediátrica.
Órgano de la Asociación Mexicana de
Infectología Pediátrica, A.C.
Órgano difusor de la Sociedad Española
de lnfectología
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2025, Number 3

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Rev Latin Infect Pediatr 2025; 38 (3)

Elizabethkingia meningoseptica sepsis in a newborn: case report

Alvarado LDA, Mascareñas SAH, Bejarano CJI, Vaquera ADN
Full text How to cite this article 10.35366/121974

DOI

DOI: 10.35366/121974
URL: https://dx.doi.org/10.35366/121974

Language: Spanish
References: 9
Page: 122-125
PDF size: 274.39 Kb.


Key words:

sepsis, newborn, opportunistic infections, neonatal intensive care unit.

ABSTRACT

Elizabethkingia meningoseptica is a gramnegative bacterium that causes opportunistic infections. It is commonly observed in the neonatal intensive care units (NICU), often resulting in patient death due to its high rate of antibiotic resistance and its prevalence in immunocompromised patients and neonates. The present case report a male product who was admitted at the NICU on his first day of life for vital signs monitoring, due to the presence of a right ventricular rhabdomyoma and suspicion of tuberous sclerosis. Abdominal distension with hemorrhage, thrombocytopenia, and altered coagulation times developed during his stay. This led to the diagnosis of sepsis, together with the identification of E. meningoseptica in a peripheral blood culture. As reported in the literature, the patient was successfully treated with levofloxacin and vancomycin. The case highlights the importance of antibiotic approach and the identification of E. meningoseptica as an emerging pathogen in the NICU, as well as the possible risk factors responsible for the development of sepsis in this patient.


REFERENCES

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  2. Sahu MK, Balasubramaniam UCB, Singh SP, Talwar S. Elizabethkingia meningoseptica: an emerging nosocomial pathogen causing septicemia in critically ill patients. Indian J Crit Care Med. 2019; 23 (2): 104-105. doi: 10.5005/jp-journals-10071-23127.

  3. Waleed MS, Amba V, Varughese AA, Pathalapati R. Elizabethkingia meningoseptica bacteremia and meningitis: a case report. Cureus. 2021; 13 (11): e19275. doi: 10.7759/cureus.19275.

  4. Bloch KC, Nadarajah R, Jacobs R. Chryseobacterium meningosepticum: an emerging pathogen among immunocompromised adults. Medicine (Baltimore). 1997; 76 (1): 30-41. doi: 10.1097/00005792-199701000-00003.

  5. González LJ, Vila AJ. Carbapenem resistance in Elizabethkingia meningoseptica is mediated by metallo-β-lactamase BlaB. Antimicrob Agents Chemother. 2012; 56 (4): 1686-1692. doi: 10.1128/AAC.05835-11.

  6. Schlapbach LJ, Watson RS, Sorce LR, Argent AC, Menon K, Hall MW et al. International Consensus Criteria for Pediatric Sepsis and Septic Shock. JAMA. 2024; 331 (8): 665-674. doi: 10.1001/jama.2024.0179.

  7. Lin JN, Lai CH, Yang CH, Huang YH. Elizabethkingia infections in humans: from genomics to clinics. Microorganisms. 2019; 7 (9): 295. doi: 10.3390/microorganisms7090295.

  8. Huang YC, Lin YT, Wang FD. Comparison of the therapeutic efficacy of fluoroquinolone and non-fluoroquinolone treatment in patients with Elizabethkingia meningoseptica bacteraemia. Int J Antimicrob Agents. 2018; 51 (1): 47-51. doi: 10.1016/j.ijantimicag.2017.05.018.

  9. Jean SS, Hsieh TC, Ning YZ, Hsueh PR. Role of vancomycin in the treatment of bacteraemia and meningitis caused by Elizabethkingia meningoseptica. Int J Antimicrob Agents. 2017; 50 (4): 507-511. doi: 10.1016/j.ijantimicag.2017.06.021.




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Rev Latin Infect Pediatr. 2025;38