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Acta de Otorrinolaringología & Cirugía de Cabeza y Cuello

ISSN 2539-0859 (Electronic)
ISSN 0120-8411 (Print)
Asociación Colombiana de Otorrinolaringología y Cirugía de Cabeza y cuello, Maxilofacial y Estética Facial (ACORL)
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2025, Number 2

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Acta de Otorrinolaringología CCC 2025; 53 (2)

Clinical characterization of invasive fungal rhinosinusitis in patients undergoing functional endoscopic surgery

Posada-Álvarez ME, Ordóñez-García R, Gayosso-Ortiz JR, Rangel-Martínez AM
Full text How to cite this article

Language: Spanish
References: 16
Page: 133-140
PDF size: 698.97 Kb.


Key words:

Sinusitis, mucormycosis, immunocompromised host, paranasal sinuses, allergic fungal sinusitis.

ABSTRACT

Introduction: Invasive fungal rhinosinusitis is an invasion of fungal microorganisms at the sinonasal level, which can extend to orbital and intracranial structures. It has a predilection for immunocompromised patients, being a cause of mortality in this population, which requires aggressive medical-surgical management. Objective: Identify the clinical characteristics of patients with invasive fungal rhinosinusitis due to mucormycosis who underwent functional endoscopic surgery. Methods: Retrospective cross-sectional study of patients from the Otorhinolaryngology Service with invasive fungal rhinosinusitis due to mucormycosis who underwent functional endoscopic surgery between January 1, 2015 and January 1, 2023 at the 20 de Noviembre National Medical Center in Mexico City. Results: A total of 16 patients with a diagnosis of invasive fungal rhinosinusitis were included, 7 women (43.75%) and 9 men (56.25%). The average age was 47 years; 68.75% had diabetes mellitus, 43.75% had arterial hypertension and 18.75% had acute lymphocytic leukemia. There were no surgical complications. Three patients (18.75%) presented prolonged neutropenia, 5 (31.25%) underwent enucleation and there was only one death. Conclusion: In patients with invasive fungal rhinosinusitis diagnosed with mucormycosis, the most common symptom was headache followed by nasal obstruction. The most common comorbidity was diabetes mellitus. Vascular disease, pneumonia and SARS-CoV-2 infection are statistically significantly associated with prolonged neutropenia.


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Acta de Otorrinolaringología CCC. 2025;53