2025, Number 2
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Acta de Otorrinolaringología CCC 2025; 53 (2)
Sudden Sensorineural Hearing Loss: Intratympanic Injection Protocol with Dexamethasone
Abuchar-Duque MJ, Tapias-Sirosi LC, Ruiz-Manco D, Ramírez-Moreno Ó, Prieto-Rivera JA
Language: Spanish
References: 29
Page: 157-165
PDF size: 729.53 Kb.
ABSTRACT
Introduction: Sudden sensorineural hearing loss (SSHL) affects thousands of people
worldwide, causing disability and reduced quality of life in adults of working age. It
is an otologic emergency requiring prompt intervention to prevent permanent hearing
loss. Despite various global treatment protocols, no consensus exists regarding
the most effective approach.
Materials and methods: This descriptive, observational,
cross-sectional study included 92 patients diagnosed with SSHL at Hospital Universitario
Clínica San Rafael between 2018 and 2022. A protocol of serial intratympanic
dexamethasone injections was implemented over three consecutive weeks, within 15
days of symptom onset. A retrospective analysis assessed hearing gain.
Results: A
polynomial correlation (R
² = 0.046) indicated a trend toward greater hearing gains
in patients treated earlier. After adjusting the raw data by excluding poor prognosis
variables such as advanced age and cardiovascular comorbidities, the trend toward
improved outcomes with earlier treatment initiation remained consistent.
Discussio:
Hearing gain was greater in patients under 65 years old, without comorbidities,
and treated earlier. The variability in recovery highlights the influence of multiple
prognostic factors and underscores the need for randomized controlled trials to clarify
treatment efficacy.
Conclusions: SSHL has a variable prognosis influenced by
multiple factors. However, patients who receive early intratympanic corticosteroid
therapy demonstrate better hearing recovery than those treated later, supporting its
role as an effective treatment option in selected cases.
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