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Archivos de Medicina de Urgencia de México

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Archivos de Medicina de Urgencia de México
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2025, Number 2-3

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Arch Med Urg Mex 2025; 17 (2-3)

Naloxone

Loria-Castellanos J, Cerón-Apipilhuasco A, Mandujano MD
Full text How to cite this article 10.35366/122680

DOI

DOI: 10.35366/122680
URL: https://dx.doi.org/10.35366/122680

Language: Spanish
References: 14
Page: 126-130
PDF size: 185.79 Kb.


Key words:

naloxone, Withdrawal Syndrome, Antagonist.

ABSTRACT

Opioid addiction is a public health crisis due to its easy access, addictive effects, and high mortality, compounded by the lack of immediate access to antagonists and limited knowledge regarding treatment dosage in cases of intoxication. The management of these patients must be gradual to avoid withdrawal syndrome, its adverse effects, and consequently the increase in mortality and hospital discharge against medical advice. Strategies have been implemented by the United States government—one of the countries most affected—for the acute management of patients; however, limited training and community willingness remain major barriers to the success of these programs.


REFERENCES

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  2. CDC’s Drug Overdose Deaths .(2023) https://nida.nih.gov/research-topics/trends-statistics/overdose-death-rates#:~:text=Overall%2C%20drug%20overdose%20deaths%20rose,overdose%20deaths%20reported%20in%202021

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  6. Saari, T. I., Strang, J., & Dale, O. Clinical Pharmacokinetics andPharmacodynamics of Naloxone. Clinical pharmacokinetics,(2024). 63(4), 397–422. https://doi.org/10.1007/s40262-024-01355-6

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  10. The U.S. FDA. (2023, 29 marzo). La FDA aprueba el primer aerosolnasal de naloxona de venta libre (Narcan 4 mg). U.S. Foodand Drug Administration

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Arch Med Urg Mex. 2025;17