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2025, Number 6

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Rev Mex Pediatr 2025; 92 (6)

The long-term consequences of Zika: impact on Honduran children and families

Sierra-Santos MA, Urquía-García AS, Rivera-Molina SE, Varela-González DM

Language: Spanish
References: 28
Page: 217-221
PDF size: 320.77 Kb.


ABSTRACT

Introduction: the Zika virus (ZIKv) epidemic in the Americas was associated with a surge in cases of microcephaly and other congenital anomalies. Honduras was among the most severely affected countries; however, data on the long-term clinical outcomes of children with Zika-associated microcephaly (ZAM) remain scarce. Objective: to describe the health status of a cohort of children with ZAM diagnosed between 2015 and 2018. Material and methods: during this period, 290 cases were registered and certified by an inter-institutional commission. For this study, 50 caregivers of children with ZAM were contacted by telephone to assess functional status, feeding, mobility, hospitalizations, and neurological development using a structured questionnaire. Results: of the 50 cases, seven (14%) had died. Among the 43 survivors, with a mean age of 7 years, 74% were completely bedridden and 94% required being carried or using a wheelchair. None were able to feed themselves. Additionally, 84% were not toilet trained, 92% required diapers, and 78% experienced constipation. Seventy-four percent had been hospitalized two or more times, primarily due to refractory seizures. Most mothers lived in vulnerable conditions and lacked institutional support. Conclusions: by school age, most children with congenital ZAM exhibit profound disability, multiple comorbidities, and marked functional dependence. Families affected by ZAM seem to require social and governmental support to access comprehensive care services aimed at improving their quality of life.


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