Martínez-Ruiz H, Nájera N, Ceballos G

Language: English
References: 7
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Cardiovascular diseases are the leading cause of morbidity and mortality worldwide, making the early identification of associated risk factors crucial.1 Insulin resistance is recognized as a pathophysiological precursor to the development of Type 2 Diabetes Mellitus (T2DM), hypertension, and its complications: ischemic heart disease, stroke, and kidney failure.

REFERENCES

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2. Chen H, Sullivan G, Quon MJ. Assessing the predictiveaccuracy of QUICKI as a surrogate index for insulinsensitivity using a calibration model. Diabetes. 2005;54 (7): 1914-1925.

3. Li C, Qi Q, Li W, Zhang X, Li L, Deng J et al. Triglycerideglucoseindex predicts major adverse cardiovascularand cerebrovascular events in non-diabetic individuals.Balkan Med J. 2025; 42 (4): 339-346.

4. Xu F, Feng Y, Zhong X. Higher triglyceride-glucoseindex is associated with increased risk of strokeamong middle-aged and elderly Chinese: a nationallongitudinal study. Sci Rep. 2024; 14 (1): 19054.

5. Sánchez‐Íńigo L, Navarro‐González D, Fernández‐Montero A, Pastrana‐Delgado J, Martínez JA. The TyGindex may predict the development of cardiovascularevents. Eur J Clin Invest. 2016; 46 (2): 189-197.

6. D’Elia L, Rendina D, Iacone R, Russo O, Strazzullo P,Galletti F. Triglyceride-glucose index, HOmeostaticModel Assessment index, and new-onset hypertension inmiddle-aged men. J Hypertens. 2026; 44 (1): 139-146.

7. Liu C, Liang D, Xiao K, Xie L. Association betweenthe triglyceride–glucose index and all cause and CVDmortality in the young population with diabetes.Cardiovasc Diabetol. 2024; 23 (1): 171.