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2026, Number 1

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Med Crit 2026; 40 (1)

Measurement of the time-velocity integral of the left ventricular outflow tract by subxiphoid window as an alternative to conventional measurement in critically ill patients

Olivares GJM, Barajas JG, Urbina VAG
Full text How to cite this article 10.35366/123037

DOI

DOI: 10.35366/123037
URL: https://dx.doi.org/10.35366/123037

Language: Spanish
References: 21
Page: 30-34
PDF size: 273.78 Kb.


Key words:

left ventricular outflow tract (LVOT), velocity time integral (VTI), subxiphoid window, echocardiography, critical care, hemodynamic monitoring.

ABSTRACT

Introduction: the left ventricular outflow tract (LVOT) velocity time integral (VTI) is an essential parameter for cardiac output assessment in critically ill patients. However, conventional apical views may be limited in patients with mechanical ventilation, altered positioning, or pleural devices. Material and methods: we conducted a retrospective observational study of 24 critically ill patients admitted between November 2024 and April 2025. LVOT VTI was measured using the apical five-chamber and modified subxiphoid views. Agreement was analyzed with the Bland-Altman method, and correlation was assessed with Pearson's coefficient. Results: mean LVOT VTI was 23.4 cm (apical) and 20.5 cm (subxiphoid). Bland-Altman analysis showed a bias of 2.51 ± 2.76, with 75% of measurements within concordance limits. Pearson's correlation demonstrated a strong association (r = 0.85, p < 0.0001). Conclusion: subxiphoid LVOT VTI measurement is a feasible and reliable alternative when conventional windows are not attainable in critically ill patients.


REFERENCES

  1. Isseh IN, Lee R, Khedraki R, Hoffman K. A critical review of hemodynamically guided therapy for cardiogenic shock: old habits die hard. Curr Treat Options Cardiovasc Med. 2021;23(5):29. doi: 10.1007/s11936-021-00903-8.

  2. Díaz-Gómez JL, Mayo PH, Koenig SJ. Point-of-Care ultrasonography. N Engl J Med. 2021;385(17):1593-1602. doi: 10.1056/NEJMra1916062.

  3. Narula J, Chandrashekhar Y, Braunwald E. Time to add a fifth pillar to bedside physical examination: inspection, palpation, percussion, auscultation, and insonation. JAMA Cardiol. 2018;3(4):346-350. doi: 10.1001/jamacardio.2018.0001.

  4. Mercado P, Maizel J, Beyls C, Titeca-Beauport D, Joris M, Kontar L, et al. Transthoracic echocardiography: an accurate and precise method for estimating cardiac output in the critically ill patient. Crit Care. 2017;21(1):136. doi: 10.1186/s13054-017-1737-7.

  5. de Backer D, Cholley BP, Slama M, Vieillard-Baron A, Vignon P, editores. Hemodynamic monitoring using echocardiography in the critically ill. 2011a ed. Berlín, Alemania: Springer; 2011. doi: 10.1007/978-3-540-87956-5.

  6. Mercadal J, Borrat X, Hernández A, Denault A, Beaubien-Souligny W, González-Delgado D, et al. A simple algorithm for differential diagnosis in hemodynamic shock based on left ventricle outflow tract velocity–time integral measurement: a case series. Ultrasound J. 2022;14(1):36. doi: 10.1186/S13089-022-00286-2.

  7. Blanco P. Rationale for using the velocity-time integral and the minute distance for assessing the stroke volume and cardiac output in point-of-care settings. Ultrasound J. 2020;12(1):21. doi: 10.1186/s13089-020-00170-x.

  8. Mitchell C, Rahko PS, Blauwet LA, Canaday B, Finstuen JA, Foster MC, et al. Guidelines for performing a comprehensive transthoracic echocardiographic examination in adults: recommendations from the American Society of Echocardiography. J Am Soc Echocardiogr. 2019;32(1):1-64. doi: 10.1016/j.echo.2018.06.004.

  9. Orde S, Slama M, Hilton A, Yastrebov K, Mclean A. Pearls and pitfalls in comprehensive critical care echocardiography. Crit Care. 2017;21(1):279. doi: 10.1186/s13054-017-1866-z.

  10. Lau YH, See KC. Point-of-care ultrasound for critically-ill patients: a mini-review of key diagnostic features and protocols. World J Crit Care Med. 2022;11(2):70-84. doi: 10.5492/wjccm.v11.i2.70.

  11. Vincent JL, de Backer D. Circulatory shock. N Engl J Med. 2013;369(18):1726-1734. doi: 10.1056/NEJMRA1208943.

  12. Paola-Paolinelli G. Principios físicos e indicaciones clínicas del ultrasonido doppler. Rev médica Clín Las Condes. 2013;24(1):139-148. doi: 10.1016/s0716-8640(13)70139-1.

  13. Zhang Y, Wang Y, Shi J, Hua Z, Xu JI. Cardiac output measurements via echocardiography versus thermodilution: a systematic review and meta-analysis. PLo SOne. 2019;14(10):e0222105. doi: 10.1371/journal.pone.0222105.

  14. Tan C, Rubenson D, Srivastava A, Mohan R, Smith MR, Billick K, et al. Left ventricular outflow tract velocity time integral outperforms ejection fraction and Doppler-derived cardiac output for predicting outcomes in a select advanced heart failure cohort. Cardiovasc Ultrasound. 2017;15(1):18. doi: 10.1186/s12947-017-0109-4.

  15. Lamia B, Ochagavia A, Monnet X, Chemla D, Richard C, Teboul JL. Echocardiographic prediction of volume responsiveness in critically ill patients with spontaneously breathing activity. Intensive Care Med. 2007;33(7):1125-1132. doi: 10.1007/s00134-007-0646-7.

  16. Villavicencio C, Leache J, Marin J, Oliva I, Rodriguez A, Bodí M, et al. Basic critical care echocardiography training of intensivists allows reproducible and reliable measurements of cardiac output. Ultrasound J. 2019;11(1):5. doi: 10.1186/s13089-019-0120-0.

  17. Gentile F, Buoncristiani F, Sciarrone P, Bazan L, Panichella G, Gasparini S, et al. Left ventricular outflow tract velocity-time integral improves outcome prediction in patients with secondary mitral regurgitation. Int J Cardiol. 2023;392:131272. doi: 10.1016/J.IJCARD.2023.131272.

  18. Pérez-Manjarrez A, García-Cruz E, Gopar-Nieto R, Jiménez-Rodríguez GM, Lazcano-Díaz E, Rojas-Velasco G, et al. Usefulness of the velocity–time integral of the left ventricular outflow tract variability index to predict fluid responsiveness in patients undergoing cardiac surgery. Echo Res Pract. 2023;10(1):9. doi: 10.1186/S44156-023-00022-Z.

  19. Babes EE, Stoicescu M, Bungau SG, Uivarosan D, Tit DM, Toma MM, et al. Left ventricle outflow tract velocity-time index and right ventricle to left ventricle ratio as predictors for in hospital outcome in intermediate-risk pulmonary embolism. Diagnostics (Basel). 2022;12(5):1226. doi: 10.3390/diagnostics12051226.

  20. Scalia IG, Farina JM, Wraith R, Brown L, Abbas MT, Pereyra M, et al. Association between echocardiographic velocity time integral ratio of mitral valve and left ventricular outflow tract and clinical outcomes post transcatheter edge-to-edge mitral valve repair. Heliyon. 2024;10(11):e32378. doi: 10.1016/j.heliyon.2024.e32378.

  21. Cheong I, Castro VO, Gómez RA, Merlo PM, Tamagnone FM. A modified subcostal view: a novel method for measuring the LVOT VTI. J Ultrasound. 2023;26(2):429-434. doi: 10.1007/s40477-022-00671-6.




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Med Crit. 2026;40