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2026, Number 3

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Acta Med 2026; 24 (3)

Efficacy of premedication with bromazepam vs placebo for reduction of preoperative anxiety in patients of the Angeles Mocel Hospital

Pazquel KI, Colín SVG, Alva ANV, Athié GJM
Full text How to cite this article 10.35366/123136

DOI

DOI: 10.35366/123136
URL: https://dx.doi.org/10.35366/123136

Language: Spanish
References: 12
Page: 198-202
PDF size: 536.38 Kb.


Key words:

premedicación, anestesia, bromazepam, ansiedad.

ABSTRACT

This study aims to evaluate the efficacy of premedication with bromazepam in reducing preoperative anxiety in patients at the Angeles Mocel Hospital. Preoperative anxiety, commonly experienced by patients due to uncertainty about the procedure, can negatively affect postoperative recovery. An observational, cross-sectional, prospective study was conducted with 185 adult patients, who were randomized to receive bromazepam or placebo. Anxiety was measured using the APAIS (Amsterdam Preoperative Anxiety and Information Scale) scale. The results showed that the group treated with bromazepam had a significantly lower mean score in anxiety (6.15) compared to the placebo group (11.5), with a statistically significant difference (p = 0.009). In addition, anxiety was higher in women. It concludes that premedication with bromazepam is effective in reducing preoperative anxiety, improving patient satisfaction and potentially favoring a faster and less complicated recovery.


REFERENCES

  1. Song SW, Jin Y, Lim H, Lee J, Lee KH. Effect of intramuscularmidazolam premedication on patient satisfaction in womenundergoing general anaesthesia: a randomised control trial.BMJ Open. 2022; 12 (6): e059915. Available in: http://dx.doi.org/10.1136/bmjopen-2021-059915

  2. Gürler H, Yilmaz M, Türk KE. Preoperative anxiety levels in surgicalpatients: A comparison of three different scale scores. J PerianesthNurs. 2022; 37 (1): 69-74. Available in: http://dx.doi.org/10.1016/j.jopan.2021.05.013

  3. Honig AJ, Galassi MG, Ogungbe OO, Uranga T, Cuevas DK.Implementation of aromatherapy, a nonpharmacological intervention,to reduce anxiety during the preoperative period. J Perianesth Nurs.2023; 38 (2): 206-212. Available in: http://dx.doi.org/10.1016/j.jopan.2022.06.011

  4. Guerrier G, Pisanu G, Baillard C. Assessing preoperative anxiety:Nurses versus health care assistants. J Perianesth Nurs. 2021; 36 (5):

  5. 514-517. Available in: http://dx.doi.org/10.1016/j.jopan.2020.09.0215. Huang YL, Xu N, Huang ST, Wang ZC, Cao H, Yu XR et al. Impact ofmusic therapy on preoperative anxiety and degree of cooperationwith anesthesia induction in children with simple congenital heartdisease. J Perianesth Nurs. 2021; 36 (3): 243-246. Available in: http://dx.doi.org/10.1016/j.jopan.2020.08.004

  6. Cortiñas M, Oya B, Caparros P, Cano G, Ibarra M, Martínez L.Premedicación con ketamina-midazolam oral en pacientes nocolaboradores en cirugía mayor ambulatoria. Rev Esp AnestesiolReanim. 2010; 57 (8): 479-485. Disponible en: http://dx.doi.org/10.1016/s0034-9356(10)70708-8

  7. Bumin Aydin G, Yüksel S, Ergil J, Polat R, Akelma FK, Ekici M,Sayın M, Odabas O. The effect of play distraction on anxietybefore premedication administration: a randomized trial. J ClinAnesth. 2017; 36: 27-31. Available in: http://dx.doi.org/10.1016/j.jclinane.2016.04.044

  8. Boussofara M. Service d’anesthésie-réanimation, Centre detraumatologie et des grands brûlés. Ben Arous, Tunis, Tunisie. Facultéde médecine de Tunis, 6, rue Omar Ibn El Ass, Khaznadar, Bardo;Tunisie; 2017.

  9. Méndez-Meneses KJ, Rebolledo-García ML, Díaz-Chacón S,Rodríguez-Vázquez LA, Acosta-Maldonado BL, Mantilla-Maya B,González-Rodríguez E, Aguilar Ponce JL et al. Validación de la Escalade Ansiedad Peroperatoria y de Información Ámsterdam (APAIS) enmujeres latinoamericanas con cáncer de mama: Estudio México-Costa Rica. Psicooncología. 2019; 16 (1): 73-88.

  10. Gómez BLM, Ocampo AF, Orozco AJA, Caicedo SJ. Eficacia de lapremedicación anestésica en el paciente pediátrico con midazolamoral y acetaminofén. Estudio observacional. Colombian Journal ofAnestesiology. 2013; 41 (1): 4-9.

  11. Andersson V, Bergstrand J, Engström A, Gustafsson S. The impact ofpreoperative patient anxiety on postoperative anxiety and quality ofrecovery after orthopaedic surgery. J Perianesth Nurs. 2020; 35 (3):260-264.

  12. Burton D, King A, Bartley J, Petrie KJ, Broadbent E. The surgical anxietyquestionnaire (SAQ): development and validation. Psychol Health.2019; 34 (2): 129-146. Available in: http://dx.doi.org/10.1080/08870446.2018.1502770




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Acta Med. 2026;24