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2026, Number 3

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Acta Med 2026; 24 (3)

Lump in sternum after postoperative radiotherapy for breast cancer

Gallardo NE, García RFM, Mancera SC
Full text How to cite this article 10.35366/123150

DOI

DOI: 10.35366/123150
URL: https://dx.doi.org/10.35366/123150

Language: Spanish
References: 5
Page: 275-278
PDF size: 1319.56 Kb.


Key words:

angiosarcoma, breast cancer, radiation therapy, sternal tumor, complication.

ABSTRACT

Osteoradionecrosis is a serious late complication of radiotherapy, a 67 year old female with a history of HER2 positive left breast cancer who underwent radical mastectomy plus chemotherapy and adjuvant radiotherapy 23 years ago, who presented solid tumor in the upper part of the sternum compatible with radionecrosis, as angiosarcoma is a differential diagnosis, the diagnostic behavior is key to provide therapeutic management, the total radiation dose is directly proportional to osteoradionecrosis. Once this complication is diagnosed, it is decided which of the various therapeutic options available is the one that can be chosen to treat it.


REFERENCES

  1. Kirova Y, Vilcoq JR, Asselain B, Sastre-Garau X, Campana F, DendaleR et al. Radiation-induced sarcomas after breast cancer: experienceof Institute Curie and review of literature. Cancer Radiother. 2006;10 (1-2): 83-90.

  2. Kirova YM, Vilcoq JR, Asselain B, Sastre-Garau X, Fourquet A.Radiation-induced sarcoma after radiotherapy for breast carcinoma: alarge-scale single-institution review. Cancer. 2005; 104 (4): 856-863.

  3. Kirova YM, Gambotti L, De Rycke Y, Vilcoq JR, Asselain B, FourquetA. Risk of second malignancies after adyuvant radiotherapy for breastcancer: a large-scale, single-institutions review. Int J Radiation OncolBiol Phys. 2007; 68 (2): 359-363.

  4. Silvestre-Donat FJ, Puente Sandoval A. Efectos adversos deltratamiento del cáncer oral. Av Odontoestomatol. 2008; 24 (1):111-121. ISSN 2340-3152.

  5. Cha C, Antonescu CR, Quan ML, Maru S, Brennan MF. Long-termresults wich resection of radiation-induced soft tissue sarcomas. AnnSurg. 2004; 239 (6): 903-909.




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C?MO CITAR (Vancouver)

Acta Med. 2026;24