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2026, Number 3

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Acta Med 2026; 24 (3)

An unusual presentation of primary cutaneous follicle center B-cell lymphoma

Tamayo GME, García RAD, Rodríguez CAA, Charli JY, Mazier AAG
Full text How to cite this article 10.35366/123159

DOI

DOI: 10.35366/123159
URL: https://dx.doi.org/10.35366/123159

Language: Spanish
References: 5
Page: 300-303
PDF size: 2727.17 Kb.


Key words:

B-cell lymphoma, non-Hodgkin lymphoma, skin neoplasm, histopathology.

ABSTRACT

Primary cutaneous B-cell lymphomas (PCBCL) represent a rare type of non-Hodgkin lymphoma, characterized by a favorable prognosis but a challenging diagnostic approach. We present the case of a male patient previously diagnosed and treated for cutaneous lymphocytoma who presented with the development of new ipsilateral dermatoses in the temporal and parietal regions, with dermoscopic findings suggestive of PCBCL. The histopathological diagnosis was established by a dermatopathologist specialized in cutaneous lymphomas and subsequently confirmed with staging studies. Treatment consisted of surgical excision followed by radiotherapy. The patient is currently in remission. Reporting rare cutaneous neoplasms in the Mexican population contributes to their recognition and to the dissemination of diagnostic and management strategies.


REFERENCES

  1. Barbati ZR, Charli-Joseph Y. Unveiling primary cutaneous B-celllymphomas: new insights into diagnosis and treatment strategies.Cancers (Basel). 2025; 17 (7): 1202.

  2. Hristov AC, Tejasvi T, Wilcox RA. Cutaneous B-cell lymphomas:2023 update on diagnosis, risk-stratification, and management. AmJ Hematol. 2023; 98 (8): 1326-1332.

  3. Martínez-Banaclocha N, Martínez-Madueño F, Caballé B, Badia J,Blanes M, Bujanda DA et al. A descriptive study of 103 primarycutaneous B-cell lymphomas: clinical and pathological characteristicsand treatment from the Spanish Lymphoma Oncology Group(GOTEL). Cancers (Basel). 2024; 16 (5): 1034.

  4. Slawinska M, Sokolowska-Wojdylo M, Olszewska B, Nowicki RJ,Sobjanek M, Zalaudek I. Dermoscopic and trichoscopic featuresof primary cutaneous lymphomas - systematic review. J Eur AcadDermatol Venereol. 2021; 35 (7): 1470-1484.

  5. Dumont M, Battistella M, Ram-Wolff C, Bagot M, de Masson A.Diagnosis and treatment of primary cutaneous B-cell lymphomas:state of the art and perspectives. Cancers (Basel). 2020; 12 (6):1497.




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Acta Med. 2026;24