Guataquira-García DO, Cardona-Maya WD

Language: Spanish
References: 25
Page: 191-196
PDF size: 189.08 Kb.

ABSTRACT

Monkeypox is an emerging viral zoonosis caused by the monkeypox virus (Mpox). Pregnant women are at increased risk of developing serious complications, including miscarriages and birth defects, with potential for vertical transmission to the fetus. The objective of this review is to analyze the available scientific evidence on the effects of Mpox infection on pregnant women and their fetuses, identifying potential maternal and fetal complications.
Mpox represents a significant risk to the health of pregnant women and their fetuses due to potential serious complications and vertical transmission of the virus. It is essential to understand its implications during pregnancy and establish effective management and prevention strategies based on the available scientific evidence.

REFERENCES

1. Bunge, E.M., Hoet, B., Chen, L., Lienert, F., Weidenthaler,H., Baer, L.R., et al., “The changing epidemiologyof human monkeypox-a potential threat? A systematicreview”, plos Negl Trop Dis, 2022, 16 (2): e0010141.

2. Titanji, B.K., Hazra, A. y Zucker, J., “Mpox clinical presentation,diagnostic approaches, and treatment strategies:a review”, jama, 2024, 332 (19): 1652-1662.

3. Velázquez-Cervantes, M.A., Ulloa-Aguilar, J.M. y León-Juárez, M., “Mpox and pregnancy: a neglected diseaseand its impact on perinatal health”, Rev Clin Esp (Barcelona),2023, 223 (1): 32-39.

4. “Monkeypox meter”. Disponible en: https://www.monkeypoxmeter.com/.

5. Alakunle, E.F. y Okeke, M.L., “Monkeypox virus: a neglectedzoonotic pathogen spreads globally”, Nat RevMicrobiol, 2022, 20 (9): 507-508.

6. Català, A., Riera, J. y Fuertes, I., “Mpox (antes viruela delmono): revisión de los aspectos clínicos, epidemiológicos,diagnósticos y terapéuticos más relevantes parael dermatólogo”, Actas Dermo-Sifiliográficas, 2023, 114(4): 318-326.

7. Najimudeen, M., Chen, H.W.J., Jamaluddin, N.A., Myint,M.H. y Marzo, R.R., “Monkeypox in pregnancy: susceptibility,maternal and fetal outcomes, and one healthconcept”, Int J mch aids, 2022, 11 (2): e594.

8. Kisalu, N.K. y Mokili, J.L., “Toward understanding theoutcomes of monkeypox infection in human pregnancy”,J Infect Dis, 2017, 216 (7): 795-797.

9. Mbala, P.K., Huggins, J.W., Riu-Rovira, T., Ahuka, S.M.,Mulembakani, P., Rimoin, A.W. et al., “Maternal and fetaloutcomes among pregnant women with human monkeypoxinfection in the Democratic Republic of Congo”, TheJournal of Infectious Diseases, 2017, 216 (7): 824-828.

10. Arranz Izquierdo, J., Molero García, J.M. y GutiérrezPérez, M.I., “Management from primary care of monkeypoxinfection (mpox) in humans”, Aten Primaria,2023, 55 (10): 102680.

11. Satapathy, P., Shamim, M.A., Padhi, B.K., Gandhi, A.P.,,Sandeep, M., Suvvari, T.K. et al., “Author correction:mpox virus infection in women and outbreak sex disparities:a systematic review and meta-analysis”, CommunMed (Londres), 2024, 4 (1): 205.

12. Petersen, E., Kantele, A., Koopmans, M., Asogun,D., Yinka-Ogunleye, A., Ihekweazu, C. et al., “Humanmonkeypox: epidemiologic and clinical characteristics,diagnosis, and prevention”, Infectious Disease Clinics ofNorth America, 2019, 3 (4): 1027.

13. Di Giulio, D.B. y Eckburg, P.B., “Human monkeypox: anemerging zoonosis”, Lancet Infect Dis, 2004, 4 (1): 15-25.

14. Dashraath, P., Nielsen-Saines, K., Rimoin, A., Mattar,C.N.Z., Panchaud, A. y Baud, D., “Monkeypox in pregnancy:virology, clinical presentation, and obstetric management”,Am J Obstet Gynecol, 2022, 227 (6): 849-861 e7.

15. Adler, H., Gould, S., Hine, P., Snell, L.B., Wong, W., Houlihan,C.F. et al., “Clinical features and management ofhuman monkeypox: a retrospective observational studyin the UK”, The Lancet Infectious Diseases, 2022, 22 (8):1153-1162.

16. Nachega, J.B., Mohr, E.L., Dashraath, P., Mbala-Kingebeni,P., Anderson, J.R., Myer, L. et al., “Mpox in pregnancy:risks, vertical transmission, prevention, andtreatment”, New England Journal of Medicine, 2024,391 (14): 1267-1270.

17. Pastuszak, A.L., Levy, M., Schick, B., Zube, C., Feldkamp,M., Gladstone, J. et al., “Outcome after maternalvaricella infection in the first 20 weeks of pregnancy”, NEngl J Med, 1994, 330 (13): 901-905.

18. Schwartz, D.A., Ha, S., Dashraath, P., Baud, D., Pittman,P.R. y Adams Waldorf, K.M., “Mpox virus in pregnancy,the placenta, and newborn”, Arch Pathol Lab Med,2023, 147 (7): 746-757.

19. Hassett, D.E., “Smallpox infections during pregnancy,lessons on pathogenesis from nonpregnant animal modelsof infection”, J Reprod Immunol, 2003, 60 (1): 13-24.

20. Mbrenga, F., Nakoune, E., Malaka, C., Bourner, J., Dunning,J., Vernet, G. et al., “Tecovirimat for monkeypoxin Central African Republic under expanded access”, NEngl J Med, 2022, 387 (24): 2294-2295.

21. Ghazy, R.M., Elrewany, E., Gebreal, A., El Makhzangy, R.,Fadl, N., Elbanna, E.H. et al., “Systematic review on theefficacy, effectiveness, safety, and immunogenicity ofmonkeypox vaccine”, Vaccines (Basilea), 2023; 11 (11).

22. Lamont, R.F., Sobel, J.D., Carrington, D., Mazaki-Tovi, S.,Kusanovic, J.P., Vaisbuch, E. et al., “Varicella-zoster virus(chickenpox) infection in pregnancy”, bjog, 2011, 118(10): 1155-1162.

23. Manicklal, S., Emery, V.C., Lazzarotto, T., Boppana, S.B. yGupta, R.K., “The ‘silent’ global burden of congenital cytomegalovirus”,Clin Microbiol Rev, 2013, 26 (1): 86-102.

24. Mlakar, J., Korva, M., Tul, N., Popović, M., Poljšak-Prijatelj,M., Mraz, J. et al., “Zika virus associated with microcephaly”,New England Journal of Medicine, 2016,374 (10): 951-958.

25. Pitts, S.I., Wallace, G.S., Montana, B., Handschur, E.F.,Meislich, D., Sampson, A.C. et al., “Congenital rubellasyndrome in child of woman without known risk factors,New Jersey, USA”, Emerging Infectious Diseases,2014, 20 (2): 307.