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2026, Number 1

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Enf Infec Microbiol 2026; 46 (1)

Direct healthcare costs for cases of sars-cov-2 infection during 2024 in neonatal patients receiving minimal intervention therapy at the National Institute of Perinatology

Galván-Contreras R, Santamaría-Alonso I, Calva-Hernández JV, Arellano-Flores MX, Trinidad-Muñoz AS, Segura-Cervantes , Luna-Gordillo R, Solórzano-Santos F
Full text How to cite this article

Language: Spanish
References: 6
Page: 14-20
PDF size: 283.90 Kb.


Key words:

covid-19, sars-cov-2, newborns, direct costs, neonatal care unit, hospital epidemiology.

ABSTRACT

Introduction. Neonates are a highly vulnerable population to respiratory infections such as sars-cov-2. This study aims to quantify the economic impact of covid-19 outbreaks in the neonatal minimal intervention therapy unit (timn) of the National Institute of Perinatology during 2024.
Methods. A retrospective observational study was conducted to analyze direct healthcare costs associated with 34 confirmed sars-cov-2 infection cases (via rt-pcr) in neonates hospitalized at timn between January and December 2024. A control group of 34 neonates without sars-cov-2 infection was selected for comparison.
Results. Infected neonates showed significantly higher healthcare costs, especially in laboratory testing, imaging, and length of hospital stay (mean: 18.5 days vs. 5.3 days in controls, p < 0.001). The total cost for infected cases was 99,620.60 pesos vs. 35,906.00 pesos for controls.
Conclusions. sars-cov-2 infection in neonates hospitalized at timn significantly increases direct healthcare costs, mainly due to longer hospital stays and additional diagnostics. These findings support the implementation of cost-effective preventive strategies in vulnerable hospital settings.


REFERENCES

  1. Centros para el Control y la Prevención de Enfermedades(cdc), covid-net, covid-19, 2021, Consultado el 13de mayo de 2025. Disponible en: https://gis.cdc.gov/grasp/COVIDNet/COVID19_3.html.

  2. Di Fusco, M., Vaghela, S., Moran, M.M., Lin, J., Atwell,J.E., Malhotra, D. et al., “Hospitalizaciones asociadas acovid-19 en niños menores de 12 años en Estados Unidos”,J Med Econ, 2022, 25 (1): 334-346. Disponible en:http://dx.doi.org/10.1080/13696998.2022.2046401.

  3. Organización Panamericana de la Salud (ops), “Prevenciónde infecciones asociadas a la atención neonatológica”,ops-oms, 2017.

  4. Wolff Sagy, Y., Feldhamer, I., Brammli-Greenberg, S. yLavie, G., “Estimating the economic burden of long-covid:the additive cost of healthcare utilization amongcovid-19 recoverees in Israel”, bmj Journals, 2023. Disponibleen: https://gh.bmj.com/content/8/7/e012588.

  5. De Rose, D.U., Pugnaloni, F., Calì, M., Ronci, S., Caoci,S., Maddaloni, C. et al., “Multisystem inflammatorysyndrome in neonates born to mothers with sars-cov-2infection (mis-n) and in neonates and infants youngerthan 6 months with acquired covid-19 (mis-c): a systematicreview”, mdpi Viruses, 2022. Disponible en: https://www.mdpi.com/1999-4915/14/4/750.

  6. Galván, R., “Informe de infecciones asociadas a la atenciónde la salud”, Instituto Nacional de Perinatología,2024.




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Enf Infec Microbiol. 2026;46