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2026, Number 4

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Acta Med 2026; 24 (4)

Prevalence of postoperative pain after the use of intrathecal opioids in subarachnoid block in patients undergoing hip fracture surgery

Tamborrell RA, Portela OJM, Villanueva SJR
Full text How to cite this article 10.35366/123496

DOI

DOI: 10.35366/123496
URL: https://dx.doi.org/10.35366/123496

Language: Spanish
References: 16
Page: 373-378
PDF size: 630.23 Kb.


Key words:

intrathecal opioid, hip fracture, acute postoperative pain, subarachnoid block, prevalence.

ABSTRACT

Introduction: inflammatory pain arises as a response to harmful stimuli, such as an incision in the skin, and is characterized by signs such as pain, heat, erythema, and swelling. After surgery, this pain can be localized, especially in the skin and deep tissues, due to the activation of A-beta nociceptive fibers. To measure pain, unidimensional scales such as the visual analog scale (VAS) are used, which is preferred by anesthesiologists for quickly and effectively assessing postoperative pain. Hip fractures in elderly patients present a high risk of mortality, with 25% of patients being operated on within 48 hours. Recovery after surgery is crucial, as it improves mobility and quality of life by 67%. Optimal analgesic techniques have been developed, such as intrathecal morphine, which provides pain relief for 12 hours postoperatively. This study aims to assess postoperative pain in patients receiving or not receiving this analgesic technique, in order to recommend its use in this population. Objective: to identify the prevalence of postoperative pain after the use of intrathecal opioids in subarachnoid block in patients undergoing hip fracture surgery. Material and methods: we conducted a case-control study with 100 patients aged 18 to 85 years, ASA I, II and III, scheduled for hip arthroplasty surgery (first time). Patients were assigned to group A (n = 50) who received intrathecal opioids such as morphine, or to group B who did not receive intrathecal opioids (n = 50). Postoperative pain was assessed using the visual analogue scale at 0, 30, 60, 90 and 120 minutes postoperatively. Results: at 120 minutes, 8% of the group without opioids presented severe pain, and 2% in the group with opioids (p = 0.434). The prevalence and severity of postoperative pain were significantly lower in the opioid group at all time points. Conclusions: intrathecal morphine reduces immediate postoperative pain but has a higher prevalence of side effects.


REFERENCES

  1. Esteve Pérez N, del Rosario Usoles E, Giménez Jiménez I, MonteroSánchez F, Baena Nadal M, Ferrer A. Analgesia postoperatoria encirugía mayor: ¿es hora de cambiar nuestros protocolos? Rev Soc EspDolor. 2009; 16 (4): 239-245.

  2. Lespasio MJ, Guarino AJ, Sodhi N, Mont MA. Pain managementassociated with total joint arthroplasty: a primer. Perm J. 2019; 23:18-169.

  3. Chou R, Gordon DB, de Leon-Casasola OA, Rosenberg JM, Bickler S,Brennan T et al. Management of postoperative pain: a clinical practiceguideline from the American Pain Society, the American Society ofRegional Anesthesia and Pain Medicine, and the American Societyof Anesthesiologists’ Committee on Regional Anesthesia, ExecutiveCommittee, and Administrative Council. J Pain. 2016; 17 (2): 131-157. doi: 10.1016/j.jpain.2015.12.008.

  4. Garimella V, Cellini C. Postoperative pain control. Clin Colon RectalSurg. 2013; 26 (3): 191-196.

  5. Jia XF, Ji Y, Huang GP, Zhou Y, Long M. Comparison of intrathecal andlocal infiltration analgesia by morphine for pain management in totalknee and hip arthroplasty: A meta-analysis of randomized controlledtrial. Int J Surg. 2017; 40: 97-108.

  6. Benhamou D. Evaluation of postoperative pain. Ann Fr Anesth Reanim.1998; 17 (6): 555-572.

  7. Teunissen AJW, Koning MV, Liefers WJ, Stap DVD, Roukema G, deBruijn B et al. A double-blind, randomised, placebo-controlled trialcomparing intrathecal bupivacaine with bupivacaine plus morphineto reduce delirium in patients with hip fractures-Salmon-Mind trialstudy protocol. BJA Open. 2023; 7: 100216.

  8. Slappendel R, Weber EW, Dirksen R, Gielen MJ, van Limbeek J.Optimization of the dose of intrathecal morphine in total hip surgery:a dose-finding study. Anesth Analg. 1999; 88 (4): 822-826.

  9. Crisman E, Appenzeller-Herzog C, Tabakovic S, Nickel CH, MinottiB. Multidimensional versus unidimensional pain scales for theassessment of analgesic requirement in the emergency department:a systematic review. Intern Emerg Med. 2024; 19 (5): 1463-1471.

  10. Foss NB, Kristensen MT, Palm H, Kehlet H. Postoperative pain after hipfracture is procedure specific. Br J Anaesth. 2009; 102 (1): 111-116.

  11. Rawal N. Intrathecal opioids for the management of post-operativepain. Best Pract Res Clin Anaesthesiol. 2023; 37 (2): 123-132.

  12. Shah OM, Bhat KM. Comparison of the efficacy and safety ofmorphine and fentanyl as adjuvants to bupivacaine in providingoperative anesthesia and postoperative analgesia in subumblicalsurgeries using combined spinal epidural technique. Anesth EssaysRes. 2017; 11 (4): 913-920.

  13. Lu Y, Hu B, Dai H, Wang B, Yao J, Yao X. Predictors of chronicpostsurgical pain in elderly patients undergoing hip arthroplasty: amulti-center retrospective cohort study. Int J Gen Med. 2021; 14:7885-7894.

  14. Dong Y, Zhang Y, Song K, Kang H, Ye D, Li F. What was theepidemiology and global burden of disease of hip fractures from 1990to 2019? Results from and additional analysis of the global burden ofdisease study 2019. Clin Orthop Relat Res. 2023; 481 (6): 1209-1220.

  15. Pereira MP, Pogatzki-Zahn E. Gender aspects in postoperative pain.Curr Opin Anaesthesiol. 2015; 28 (5): 546-558.

  16. Motaghedi R, Bae JJ, Memtsoudis SG, Kim DH, Beathe JC, Paroli Let al. Association of obesity with inflammation and pain after totalhip arthroplasty. Clin Orthop Relat Res. 2014; 472 (5): 1442-1448.




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Acta Med. 2026;24