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2026, Number 4

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Acta Med 2026; 24 (4)

Comparison of semaglutide versus hygienic-dietary intervention for weight control in the Mexican population: a retrospective study of outpatient clinical practice

Flores GMA
Full text How to cite this article 10.35366/123497

DOI

DOI: 10.35366/123497
URL: https://dx.doi.org/10.35366/123497

Language: Spanish
References: 11
Page: 379-382
PDF size: 554.59 Kb.


Key words:

obesity, semaglutide, risk factor.

ABSTRACT

Introduction: obesity is one of the most important risk factors linked to the increase in cardiovascular diseases, type II diabetes, hypertension, arthritis, and some types of cancer. Furthermore, it is considered the most prevalent non-communicable disease in the world. In recent decades, obesity and overweight have become a public health problem that is increasing every day, both in developed and developing countries. Following this trend, in Mexico, the 2022 National Health and Nutrition Survey (ENSANUT 2022) showed that the prevalence of obesity was 41.0% in women and 32.3% in men. These data reaffirm that obesity is a critical health problem in Mexico, with a high prevalence and association with multiple comorbidities. Objective: to compare the efficacy of semaglutide versus dietary hygiene interventions in reducing body weight at three months. Material and methods: a retrospective study was carried out in 66 overweight or obese patients, comparing weight loss in two groups: semaglutide vs. diet-exercise. Results: the semaglutide group lost significantly more weight (12.7 ± 5.9 kg) than the non-pharmacological group (5.1 ± 2.9 kg), p < 0.000001. Conclusion: semaglutide has shown greater efficacy than non-pharmacological intervention in the Mexican population in the short term.


REFERENCES

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Acta Med. 2026;24