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2026, Number 2

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Rev Mex Pediatr 2026; 93 (2)

Risk factors associated with the development of renal scarring in pediatric patients with recurrent urinary tract infections

Galeana BFÁ, Zurita-Cruz J, Zepeda-Martínez CC, Alegría-Torres GA

Language: Spanish
References: 18
Page: 58-63
PDF size: 774.19 Kb.


ABSTRACT

Introduction: recurrent urinary tract infections (rUTI) is defined as three episodes in six months or four in one year and is associated with an increased risk of renal scarring and damage. Objective: to identify risk factors associated with the development of renal scarring in pediatric patients with rUTI. Material and methods: this was a longitudinal, retrospective study of patients treated at a tertiary-level pediatric nephrology service. The following variables were analyzed: sex, age, nutritional status, isolated microorganism, kidney size, etiology of UTI. Results: forty-eight patients were included, 43 of whom were women, with a median age of 48 months; 89% had Escherichia coli infection. Thirty-nine percent presented with vesicoureteral reflux, 25% with urinary obstruction, and 14.5% with neurogenic bladder. Eighty-three percent developed renal scarring and 62% with kidney damage, with a decrease in 47% of these cases. The only factor associated with renal scarring and damage was the detection of abnormalities on renal ultrasound. Conclusions: rUTI are associated with a high frequency of nephrotic scarring and decreased GFR. Identifying abnormalities on renal ultrasound is key to detecting patients at higher risk of kidney damage.


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