2026, Number 1
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Dermatología Cosmética, Médica y Quirúrgica 2026; 24 (1)
Anatomical variability of the hair follicle cycle and hair growth dynamics
Pérez-Romero AG, Sánchez-Dueñas LE, Aceves-Villalvazo MA, Morfín-Hernández L
Language: Spanish
References: 18
Page: 99-105
PDF size: 220.47 Kb.
ABSTRACT
BACKGROUND: The human hair follicle is a highly specialized
organ whose cyclic activity determines the structural
characteristics of the hair shaft according to the anatomical
region. Despite its clinical relevance, quantitative data
regarding growth kinetics and cycle duration remain dispersed
across medical and forensic literature.
OBJECTIVE: To integrate and systematize available evidence
on the anatomical variability of the follicular cycle, hair elongation
rates, and the distribution of terminal versus vellus
hair, contrasting adult physiology with pediatric follicular
maturation.
RESULTS: The review establishes that the scalp exhibits the
most prolonged cycle (anagen phase of 2–8 years) with a
consistent growth rate of 10 mm/month. In contrast, regions
such as eyebrows and eyelashes display brief growth phases
(2–3 months and 4–10 weeks, respectively), functionally
adapted for ocular protection. Complementary forensic studies
reveal differential growth rates in the axilla (≈0.4 mm/day)
and pubis (≈0.3 mm/day). In the pediatric population, growth
velocity shows an age-dependent evolution, accelerating
from 0.22 mm/day in infants to 0.38 mm/day by age three.
CONCLUSIONS: Human hair biology is defined by a functional
duality: it follows a strict regional anatomical programming
but retains plasticity in response to the microenvironment.
The final clinical length depends not only on growth kinetics
but is also modulated by molecular signaling networks
(Wnt/BMP), neuroendocrine balance, and the cumulative
impact of the exposome on the hair fiber.
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