2026, Number 1
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Dermatología Cosmética, Médica y Quirúrgica 2026; 24 (1)
Topical crisaborole as a steroid-sparing therapy in alopecia areata: a case report
Rosas-Morett MT, Cerda-Contreras KL
Language: Spanish
References: 10
Page: 130-134
PDF size: 327.03 Kb.
ABSTRACT
Alopecia areata is an autoimmune inflammatory disease
mediated by T lymphocytes, its first-line treatment includes
topical and intralesional corticosteroids. However, its use
may be limited in patients with adverse effects secondary
to the systemic use of steroids. We present the case of
a 74-year-old female patient with recurrent alopecia areata,
who developed iatrogenic Cushing’s syndrome and secondary
anemia after the use of systemic corticosteroids, which
motivated the search for a safe therapeutic alternative.
Treatment was initiated with topical 2% crisaborole applied
every 12 hours, with complete clinical remission after two
months of treatment, without adverse events. This case
suggests that crisaborole may represent an effective and
safe therapeutic option as a steroid-sparing treatment in
patients with alopecia areata and contraindications to the
use of corticosteroids.
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