Vidal BJ, Hernández CD, Pichardo VL, Nanita EF, Cochón AM

Language: Spanish
References: 5
Page: 302-305
PDF size: 281.99 Kb.

ABSTRACT

Sarcoidosis is a multisystem disorder of unknown etiology characterized histopathologically by noncaseating granulomas. While it predominantly affects young adults, its clinical expression in the skin is highly polymorphic, manifesting as macules, papules, plaques, subcutaneous nodules, lupus pernio, or infiltrative scars. Current therapeutic strategies prioritize corticosteroids; specifically, intralesional triamcinolone acetonide has proven effective in modulating inflammation and achieving lesion resolution.
We report a 42-year-old female with cutaneous sarcoidosis localized to the nasal region. The patient was treated with intralesional triamcinolone acetonide (10 mg/mL), resulting in a favorable clinical response and significant flattening of the lesions.
The diagnostic complexity of cutaneous sarcoidosis lies in its “great imitator” nature. A thorough clinical evaluation supported by histopathological confirmation is essential to identify sarcoid granulomas and differentiate them from other dermatological conditions.
The management of cutaneous sarcoidosis necessitates a comprehensive approach, including multidisciplinary screening to rule out systemic involvement. Intralesional corticosteroid injections remain a safe and effective first-line therapy for localized disease, significantly improving both clinical outcomes and the patient’s quality of life.

REFERENCES

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