medigraphic.com
SPANISH

Revista Mexicana de Trasplantes

ISSN 3122-3893 (Electronic)
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
    • Send manuscript
  • Policies
    • Políticas éticas
    • Políticas editoriales generales
    • Políticas de revisión de manuscritos
    • Políticas de acceso abierto
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2026, Number 2

<< Back Next >>

Rev Mex Traspl 2026; 15 (2)

Beyond the lung: disseminated nocardiosis in a kidney transplant recipient

Bautista-Reyes E, Alvarado-Robles LM, Moragrega-Urías RA, Palacios-Rojas AD, Matias-Carmona M, Chacón-Hernández SE, Cano-Cervantes JH, Fernández-Vivar C
Full text How to cite this article 10.35366/124004

DOI

DOI: 10.35366/124004
URL: https://dx.doi.org/10.35366/124004

Language: Spanish
References: 7
Page: 86-88
PDF size: 1093.16 Kb.


Key words:

Nocardia infections, opportunistic infections, kidney transplantation.

ABSTRACT

Introduction: disseminated nocardiosis is a rare and potentially fatal opportunistic infection in kidney transplant recipients. Case presentation: a 31-year-old man with a kidney transplant presented with recurrent cytomegalovirus (CMV) infection. He had a chronic cough, a pulmonary mass, osteomyelitis, and cerebral microabscesses. Isolation of Nocardia brasiliensis in multiple cultures confirmed the diagnosis. He received trimethoprim/sulfamethoxazole and linezolid, with clinical and graft function improvement. Conclusions: nocardiosis should be suspected in transplant recipients with persistent pulmonary lesions and multisystem involvement.


REFERENCES

  1. Gibson M, Yang N, Waller JL, Young L, Bollag WB, Kheda Met al. Nocardiosis in renal transplant patients. J Investig Med. 2022; 70 (1): 36-45. doi: 10.1136/jim-2021-001783.

  2. Peleg AY, Husain S, Qureshi ZA, et al. Risk factors, clinicalcharacteristics, and outcome of Nocardia infection in organtransplant recipients: a matched case-control study. Clin InfectDis. 2007; 44 (10): 1307-1314. doi: 10.1086/514340.

  3. Coussement J, Lebeaux D, van Delden C, et al. Nocardiainfection in solid organ transplant recipients: a multicenterEuropean case-control study. Clin Infect Dis. 2016; 63 (3): 338-345. doi: 10.1093/cid/ciw241.

  4. Abers MS, Filice GA. Nocardiosis. In: Longo DL, Fauci AS,Kasper DL, Hauser SL, Jameson J, Loscalzo J, Holland SM,Langford CA, eds. Harrison’s Principles of Internal Medicine.22nd ed. McGraw Hill; 2025.

  5. Restrepo A, Clark NM; Infectious Diseases Communityof Practice of the American Society of Transplantation.Nocardia infections in solid organ transplantation: guidelinesfrom the Infectious Diseases Community of Practice of theAmerican Society of Transplantation. Clin Transplant. 2019;33 (9): e13509. doi: 10.1111/ctr.13509.

  6. Lebeaux D, Freund R, van Delden C, et al. Outcome andtreatment of nocardiosis after solid organ transplantation: newinsights from a European study. Clin Infect Dis. 2017; 64 (10):1396-1405. doi: 10.1093/cid/cix124.

  7. Yetmar ZA, Challener DW, Seville MT, Bosch W,Beam E. Outcomes of nocardiosis and treatment ofdisseminated infection in solid organ transplant recipients.Transplantation. 2023; 107 (3): 782-791. doi: 10.1097/TP.0000000000004343.




CC BY-NC-ND

2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Rev Mex Traspl. 2026;15