2006, Number 2
Comparative effectiveness between 0.1% metilprednisolone aceponate and 0.5% betamethasone dipropionate among children whit nonretractable prepuce.
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ABSTRACTObjective: To compare clinical improvement between treatment with metilprednisolone aceponate vs. betamethasone dipropionate among children with nonretractable prepuce.
Material and methods: Between August 2001 and November 2002, we carried out a double blind and controlled clinical trial in 34 children with a diagnosis of nonretracable prepuce. Children were randomly assigned to one of the following groups and topical treatment was administered: Group A; metilprednisolone aceponate 0.1% and Group B; betamethasone dipropionate 0.05%.
Results:2 = 0.2; p = 0.6).
Conclusions: The percentage of clinical improvement was similar between the two groups of topical steroid treatment administered.
Haynes RC. Adrenocorticotropic hormone; adrenocortical steroids and their synthetic analogs: inhibitors of the synthesis and actions of adrenocortical hormone. In Gilman AG, Rall TW, Nies AS, Taylor P. editores .Goodman and Gilman´s The Pharmacological basis of therapeutics. New York 1992; Mc Graw Hill. p. 1443.