Gallegos HJF, Pichardo RP

Language: Spanish
References: 17
Page: 13-17
PDF size: 62.24 Kb.

ABSTRACT

Introduction: Standard neck treatment in patients with upper aero-digestive tract epidermoid carcinoma (UADTEC) without palpable cervical nodes (cN0) is elective-selective neck dissection (ND); nevertheless, in patients without metastasis in the dissection specimen (pN0) ND has no impact on regional control. Approximately 70% of cN0 patients are pN0 and are exposed to morbidity; in these patients, lymphatic mapping and sentinel node biopsy (LMSNB) could be an alternative for neck staging. The objective of this study was to know the feasibility of LMSNB technique performed with blue dye and Rhenium colloid in UADTEC patients. Methods: The day prior to surgery, 3mCi of Rhenium colloid were injected peritumorally (p.t.) into 15 patients with T1-2, N0, and lymphogammagraphy of >4-mm thickness of oral tongue was done immediately at 1 and 2 h after injection; site of sentinel node (SN) was identified in neck skin with ink. Twenty min prior to surgery, 1 mL of blue patent V was injected into the same site. Neoprobe 2000^TM was used to identify the hot spot during surgery. All hot and/or blue nodes were considered SN and studied by frozen section. All patients were submitted to supra-omohioid neck dissection Results: Lymphogammagraphy showed at least 1 SN in all 15 patients. In two patients, SN was identified at stage IV. ed to measure attitudes toward the entire process. Validation of the attitude survey may become a valuable source of information for detecting opportunities in this field. During surgery, at least 1 SN was identified in all patients (success index = 100%), 3/15 patients showed metastasis in GC, and none of the 12 patients with negative SN had metastasis in non-sentinel nodes (no false negatives). Conclusions: It is possible to identify SN in patients with UADT carcinoma; SN predicts non-sentinel nodes status in neck.

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