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ISSN 0185-3252 (Print)
Revista de la Asociación Médica del Centro Médico ABC

2007, Number 3

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An Med Asoc Med Hosp ABC 2007; 52 (3)

Comparison propranolol and midazolam treatment of preoperative anxiety

Boone EAC, Guadarrama QF, Sánchez RJP, Díaz AMA, Rodríguez RJ, Zamora LJ

Language: Spanish
References: 9
Page: 114-117
PDF size: 102.45 Kb.


ABSTRACT

The effectiveness of propranolol as pre-anesthetic medication to treat pre-operative anxiety was evaluated in 60 healthy patients, ASA I classification, using Anxiety Analog Visual Scale (AVS) undergoing ambulatory surgery. In this randomized study patients received one of the following pre-anesthetic medications: 40 mg oral propranolol (n = 20) , 7.5 mg oral midazolam (n = 20), or placebo (n = 20). VAS results and hemodynamic parameters such as blood pressure and heart rate were recorded before and after anesthetic induction. No significant difference was found between midazolam and propranolol for the treatment of pre-operative anxiety. The use of propranolol in patients undergoing ambulatory surgery did not have any central nervous system depression or amnesic periods. Symptoms of anxiety such as tachycardia, sweating, and involuntary movements were eliminated.


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