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Ginecología y Obstetricia de México

Federación Mexicana de Ginecología y Obstetricia, A.C.
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2006, Number 09

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Ginecol Obstet Mex 2006; 74 (09)

Vulvar cellular angiofibroma. A report of a case and bibliographic review

Hernández MA, Estrada MI, Márquez IP, Alanis FJ, Pacheco PR
Full text How to cite this article

Language: Spanish
References: 6
Page: 499-502
PDF size: 424.57 Kb.


Key words:

cellular angiofibroma, vulva, lipoma, angiomyofibroblastoma, aggresive angiomixoma, diagnosis, treatment.

ABSTRACT

The vulvar cellular angiofibroma is a rare mesenchymal tumor. It can be located in many places, but it is more frequent in the vulvar area. It is characterized for being of superficial and slow-growth and for having low propensity of local recurrence. It was described in 1997 by Nucci and it had been reported 51 cases worldwide, from which 18 had vulvar location. This is the first case in Mexico City. It was found in a 36 years-old woman. The specimen was processed by structural and immunohistochemical analysis. Misdiagnosis is common and it can be confounded with spindle cell lipoma, hydrocele of the canal of Nuck, fibromas, angiomyofibroblastoma and many other mesenchymal tumors. It should be distinguished from the aggresive angiomixoma. To improve the clinical diagnosis and treatment, it is very important to have in mind this relatively new entity.


REFERENCES

  1. Hernández-Monge A, Estrada-Moscoso I, Alanis-López P, Villanueva LA. Angiomiofibroblastoma vulvar, informe de un caso y revisión de la literatura. Ginecol Obstet Mex 2000;68:31-34.

  2. Nucci MR, Granter SR, Fletcher CDM. Cellular angiofibroma: a benign neoplasia distinct from angiomyofibroblastoma and spindle cell lipoma. Am J Surg Pathol 1997;21:636-44.

  3. Iwasa Y, Fletcher CD. Cellular angiofibroma: clinicopathologic and immunohistochemical analysis of 51 cases. Am J Surg Pathol 2004;28(11):1426-35.

  4. Kerkuta R, Kennedy CM, Benda JA, Galask RP. Vulvar cellular angiofibroma: a case report. Am J Obstet Gynecol 2005;193(5):1750-2.

  5. Begin LR, Clement PB, Kirk ME, Jothy S, et al. Aggressive angiomyxoma of pelvic soft parts. A clinicopathologic study of nine cases. Hum Pathol 1985;16:621-8.

  6. Micheletti AM, Silva AC, Nascimento AG, Da Silva CS, et al. Cellular angiofibroma of the vulva: case report with clinicopathological and immunohistochemistry study. Sao Paulo Med J 2005;123(5):250-2.




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Ginecol Obstet Mex. 2006;74