Muñoa PJA, Serrano LJ, Cossío ZA, Serrano RE, Gregorio HJ

Language: Spanish
References: 13
Page: 56-62
PDF size: 52.09 Kb.

ABSTRACT

Introduction: There are several studies about ophthalmologic manifestations caused by the extracranial carotid disease. This disease has been studied accurately in regard to cerebral vascular events, nevertheless there are few studies related to the carotid stenosis degree and to the presence of ophthalmologic signs and symptoms.
Objective: Our research intends to determine the relationship between the carotid disease and the ophthalmologic manifestations.
Material and method: A study was performed in 100 patients older than 65 years with high risk in peripheral disease through carotid US Doppler duplex.
Results: Out of the 100 patients with some risk in carotid disease, there were 57 patients with some stenosis degree. The patients were divided into three groups: those who presented stenosis from 50 to 99%, another group with ranks from 16-49% and finally those with stenosis of 15% or less. All patients underwent ophthalmologic exploration. Group A was formed by 19 patients, among them seven presented some type of ophthalmologic manifestation. Within group B, out of the 13 patients, six showed ophthalmological signs and symptoms related with carotid disease. As to the 25 patients of group C, only two had some ophthalmologic manifestation.
Conclusion: Our research showed that patients with stenosis from 20 to 99% presented 40.6% of ophthalmologic manifestations, which in time may produce blindness or visual damage through the years.

REFERENCES

1. Huber TS, Seeger JM. Dartmouth Atlas of Vascular Health Care review: impact of hospital volume, surgeon volume, and training on outcome. Vasc Surg 2001; 34: 751-6.

2. Fuster V, Badimon Jl, Chesebro JH. Atherothrombosis and clinic therapeutic approaches. Vasc Med 1998; 3: 231-9

3. Majluf A. Aterotrombosis. Hospital General Regional "Gabriel Mancera" del IMSS.

4. Stary HC, Chandler AB, Dinsmore RE, A definition of advanced types of atherosclerosis. American Heart Association. Circulation 1995; 92: 1355-74.

5. De Meyer GRY. Vascular endothelial dysfunction. Prog Cardiovasc Dis 1997; 39: 325-42.

6. Barenson GS, Sirinivasan RB. Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults: The Bogalusa Heart Study. N Engl J Med 1998; 4: 1650-6.

7. Ruggeri ZM. Mechanisms initiating platelet thrombus formation. Thromb Haemost 1997; 78: 611-16.

8. Gachet C, Hechler B. Activation of ADP receptors and platelet function. Thromb Haemost 1997; 78: 271-5.

9. Coller BS. Platelet GPIIb/IIIa antagonists: The first anti-integrin receptor therapeutics. J Clin Invest 1997; 99: 1467-71.

10. Fisher MF. Occlusion of the internal carotid artery. Arch Neurol Psychiatry 1951; 65:346.

11. Hollenhorst RW. Significance of bright plaques in the retinal arterioles. Trans Am Ophthalmol Soc 1961; 59: 252.

12. Kearns TP, Hollenhorst MF. Venous-stasis retinophaty of occlusive disease of the carotid artery. Mayo Clin Proc 1963; 38: 304.

13. Lovelace T. Optimizing duplex follow-up in patients with an asymptomatic internal carotid artery stenosis of less than 60%. Vascular Surg 2001, 33(1).