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2007, Number 3

Gac Med Mex 2007; 143 (3)

¿Es posible curar a un paciente con micosis fungoides? Informe de un caso

Guillermo-Villanueva VA, Ruiz-Delgado GJ, Tarín-Arzaga LC, Gómez-Almaguer D
Full text How to cite this article

Language: Spanish
References: 6
Page: 249-251
PDF size: 54.81 Kb.


Key words:

T-cell non Hodgkin lymphoma, mycosis fungoides, Sezary Syndrome.

ABSTRACT

Sezary syndrome (SS) and mycosis fungoides (MF) are a group of non Hodgkin lymphomas that originate from T-lymphocytes and involve mostly the skin. These entities are generally non treatable and patient prognosis remains poor even with the advent of current treatment schedules. Complete remissions are seldom observed. For this reason, bone marrow transplant has been used as a treatment option. The high mortality associated with this procedure has turned reduced intensity conditioning stem cell transplant into a treatment option. This case study illustrates how stem cell transplant offers complete remission of this type of lymphomas.


REFERENCES

  1. Siegel, RS, Pandolfino, T, Guitart J. Primary cutaneous T-cell lymphoma: review and current concepts. J Clin Oncol 2000;18:2908.

  2. Beutler E, Lichtman A, Coller S, Kipps J, Feligsohn U. Williams Hematología. Marbán Libros S.L. Madrid, España. 2005.

  3. Guitart J, Wickless SC, Oyama Y, Kuzel TM, Rossen ST, Traynor A, et al. Long-term remission after allogenic hematopoietic stem cell transplantation for refractory cutaneous T-cell lymphoma. Arch Dermatol. 2002;138:1359-1365.

  4. Molina A, Zain J, Arber DA, Angelopolou M, O‘Donnell M, Murata-Collins J, et al. Durable clinical, cytogenetic, and molecular remissions alter allogeneic hematopoietic cell transplantation for refractory Sesary syndrome and mycosis fungoides. J Clin Oncol. 2005;23:6163-6171.

  5. Soligo D, Ibatici A, Berti E, Morandi P, Longhi E, Venegoni L, et al. Treatment of advanced mycosis fungoides by allogeneic stem-cell transplantation with a nonmyeloablative regimen. Bone Marrow Transplant. 2003;31:663-666.

  6. Ruiz Argüelles G, Gómez Almaguer D, Suárez González L. El método mexicano para trasplante de células totipotenciales hematopoyéticas rompió dogmas y favoreció a muchos pacientes. Med Int Mex 2006;22:128-138.




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Gac Med Mex. 2007;143