Miranda RJA, Rico MG, Linares GLM, Delgado CEA, Flores PN

Language: Spanish
References: 15
Page: 85-89
PDF size: 137.25 Kb.

ABSTRACT

Introduction: This work presents clinical evolution and functional outcome of patients with histologic diagnosis of Muscle-aponeurotic aggressive fibromatosis in 10 years of follow up in the National Rehabilitation Institute. Material and methods: We performed a descriptive, retrospective, cross sectioned clinical trial in the Bone Tumour Department. We reviewed the clinical and radiological files from 1996 to 2006. Inclusion criteria: both genres, any age, clinical and histological diagnosis. Exclusion criteria: incomplete file, lost to follow up, other diagnosis. Elimination criteria: Death during trial period. Analyzed variables. Age, genre, occupation, birth place, school degree, anatomic situation, signs and symptoms, time of follow up, treatment, relapses. We used statistical computed system Excel 2007, with central trend descriptive variables. Results: Eleven patients (mean age 24.36; SD 18.32, 1-61 years), 9 female (81.8%) 2 male; birth place: Mexico City 7 (63.63%), Puebla 1, Toluca 1, South Baja California 1 and Chiapas 1. Anatomic situation: Pelvis 6 (54.54%), thoracic and gluteus 3. Pain and presence of a mass 10 (90.9%), range of motion limitation 5, edema and erithema 1. Relapses 6 (55%). Treatment: broad resection 3 patients, marginal resection 6 patients, radical resection 2 patients. Conclusions: If clinical suspicion of Muscle-aponeurotic fibromatosis appears, one should start protocol work up: laboratory, radiographic assessment, nuclear medicine, biopsy and histologic and immune-histochemistry. One should perform broad resections aiming to preserve the most possible extremity tissue disease free.

REFERENCES

1. McFarlane J: Clinical reports on the surgical practice of Glasgow Royal Infirmary. Glasgow (Scotland): D. Robertson; 1832: 63-7.

2. Stout AP: Fibrosarcoma, well-differentiated (agresssive fibromatosis). Cancer 1954; 7: 952.

3. Shih HA, Hornicek FJ, DeLaney TF: Fibromatosis: current strategies for treatment. Curr Opin Orthop 2003; 14: 405-12.

4. Nichols RW: Desmoid tumors: A report of 31 cases. Arch Surg 1923; 7: 27-36.

5. Enzinger FM, Shiraki M: Musculoaponeurotic fibromatosis of the shoulder girdle (extra-abdominal desmoid). Analysis of thirty cases followed of ten of more years. Cancer 1967; 20: 1131-40.

6. Weiss SW, Goldblum JR, Enzinger and Weiss’s. Fibromatoses. Soft tissue tumors. Mosby. St. Louis, Missouri. United States of America. Fourth edition. 2001; 10: 309-46. Chapter 10.

7. Bach C: Desmoid tumors of the abdominal wall in children. An Pediatr 1972; 11: 239.

8. Salmon M: Desmoid tumor of the abdominal wall in a young boy. Ann Chir Infant 1964; 5: 107.

9. Brockman DD: Congenital desmoid of the abdominal wall. J Pediatr 1947; 31: 17.

10. Rodriguez-Bigas MA, Mahoney MC, Karakousis CP, et al: Desmoid tumors in patients with familial adenomatous polyposis. Cancer 1994; 74: 1270.

11. Alman BA, Goldberg MJ, Naber SP, et al: Aggressive fibromatosis. J Pediatric Orthop 1992; 12: 1-10.

12. Reitamo JJ, Hayry P, Nykyri E, et al: The desmoid tumor. Incidents, sex, age and anatomical distribution in the population. Am J Clin Pathol 1982; 77: 665-73.

13. Burke AP, Sobin LH, Shekitka DM, et al: Intraabdominal fibromatosis: a pathologic analysis of 130 tumors with comparison of clinical subgroups. Am J Surg Pathol 1990; 14: 335-41.

14. Mike O, Seegenschmiedt MH: Radiation therapy for aggressive fibromatosis (desmoid tumors): results of national patterns of care study. Int J Radiant Oncol Biol Phys 2005; 61: 882-91.

15. Hutchinson JR, Norris DG, Schnaufer L: Chemotherapy: a succssesful application in abdominal fibromatosis (letter to the editor). Pediatrics 1979; 63: 157.