Padilla RN, Díaz GR, Muñoz RM

Language: Spanish
References: 9
Page: 152-156
PDF size: 120.19 Kb.

ABSTRACT

We studied urinary tract infection 100 children with age between 1 and 15 years, all of them had a urine culture with a bacteriological count higher than 100,000 CFU/mL. They were randomized in two groups, the group I received fosfomycin/trometamol (one dose one day) and the group II received amoxacillin, in three daily doses for 10 days. Clinical evaluation were done at the 3, 5, 7, 9 and 11 days after to begin the treatment; we evaluate the improvement of the clinical data and the urine culture was repited three days after ending the treatment. In group I we obtained 44 (97.7%) success and 1 (2.3%) clinical failure; in the bacteriological efficacy we obtained 40 (88.9%) success and 5 (11.1%) failures. The group of amoxacillin was formed by 55 patients; the clinical efficacy was obtained in 48 (87.3%) success and 7 (12.7%) failures, after 11 days of follow up; in the bacteriological efficacy, we obtained 38 (69.1%) success and 17 (30.9%) failures. In the group fosfomycin/trometamol there was a more quickly improvement (3-5 days) in comparison with 5-7 days obtained with amoxacillin. We concluded that the fosfomycin/trometamol is a good option in the treatment of UTI noncomplicated and the patients complied the treatment.

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