Echegoyen CR, Mendoza PD, Velázquez MME

Language: Spanish
References: 12
Page: 107-113
PDF size: 118.55 Kb.

ABSTRACT

Introduction and objective: This is a retrospective study of carcinoid tumors of the lung diagnosed from 1997 to 2006 at the Ismael Cosío Villegas National Institute of Respiratory Diseases, a concentration hospital in México City, in order to evaluate possible differences between typical and atypical carcinoid.
Results: We detected sixteeen carcinoid tumors, nine typical, and seven atypical. There were 14 females; 3 females were smokers in the typical group. The clinical course prior to presentation went from six months to four years for typical carcinoids and six months to three years for atypical carcinoids. The symptoms were cough, haemoptysis, thoracic pain, "asthma", recurrent pneumonia, weight loss, and respiratory insufficiency. One had tuberculosis and was treated before diagnosing the carcinoid. Chest X-rays showed pneumonia, atelectasis and tumor images. CT scans showed enlarged mediastinal lymph nodes (MLN) in six patients. Bronchoscopy and biopsy were diagnostic. Two cases were in the trachea; one was resected and end to end anastomosis performed, the other was resected with biopsy forceps; other procedures included two pneumonectomies, five bilobectomies, five lobectomies and one bronchial sleeve resection; one patient refused surgery. The 6 patients with enlarged MLN had mediastinal dissection; the nodes were negative.
Discussion and conclusions: In our clinical material, the majority of carcinoids affect women; atypical carcinoids tend to occur in slightly younger people than typical cases. There was no relationship between tumors and smoking. Early clinical, imaging, bronchoscopic and pathologic diagnosis are important for early surgical resection and preservation of lung function; MLN should be routinely dissected, as in other cases of lung cancer. Broncoscopic resection is restricted to cases unable to undergo curative procedures.

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