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Revista Mexicana de Oftalmología

Anales de la Sociedad Mexicana de Oftalmología y Archivos de la Asociación Para Evitar la Ceguera en México
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2006, Number 3

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Rev Mex Oftalmol 2006; 80 (3)

Factores pronósticos y determinación de pérdida de células endoteliales en queratoplastia penetrante

Covarrubias-Espinosa EP, Ozorno-Zarate J, Naranjo-Tackman R
Full text How to cite this article

Language: Spanish
References: 13
Page: 145-149
PDF size: 512.35 Kb.


Key words:

Penetrating keratoplasty, endothelial cells, specular microscopy.

ABSTRACT

Introduction: Penetrating keratoplasty is a procedure for optic and therapeutic purpose. Corneal clarity following penetrating keratoplasty depends on the maintenance of healthy endothelial cells. The loss of endothelial cells following surgery has been demonstrated and depends on various factors.
Objective: To measure endothelial cell count and pachymetry in corneal transplanted patients and determine risk factors to prevent endothelial cells loss.
Methods: Specular microscopy was realized on the 15th and 30th day after surgery in patients with corneal transplant. Cell count and corneal thickness was determined.
Results: We found an endothelial cell loss of 15.93% after surgery. No relation between endothelial cell loss and diagnosis or age of the receptor could be determined.
On the other hand a relation between endothelial cell loss and time of enucleation and graft setting was found.
Conclusions: Penetrating keratoplasty must be done as soon as possible. Unfortunately it is difficult to obtain the graft. We must be aware of the risk factors which predispose to corneal rejection in order to prevent it.


REFERENCES

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  2. Bourne WM. Examination and photography of donor corneal endothelium. Arch Ophthalmol 1976, 94:1799.

  3. Bourne WM, Hodge DO, Nelson LR. Corneal endothelium five years after transplantation. Am J Ophthalmol 1994; 118:185-96.

  4. Ing JJ, Ing HH, Nelson LR y col. Ten year postoperative results of penetrating keratoplasty.Opthalmology 1998; 105:1855-65.

  5. Paufique L, Sourdille GD, Offret G. Les greffes de la cornée. Paris, Mason & cie, 1948, pp 131-136.

  6. Maumenee AE. The influence of donor recipient sensitization on corneal grafts. Am J Ophthalmol 1951, 34:142-152.

  7. Khodadoust AA, Silverstein AM. Transplantation and rejection of individual cell layers of the cornea. Invest Opthalmol 1969; 8:180-195.

  8. Alldredge C, Jay H. Clinical types of corneal transplant rejection. Arch Opthalmol 1981; 99:599-604.

  9. Gibbs DC, Batchelor JR, Werb A. The influence of tissuetype compatibility on the fate of ful-thickness corneal grafts. Trans Opthalmol Soc UK 1974; 94:101-126.

  10. Laurence W, Walter JS. Clinical specular microscopy of corneal endothelial rejection. Arch Ophthalmol 1983; 101:1387-1391.

  11. Culbertson W, Abbot R, Forster R. Endothelial cell loss in penetrating keratoplasty. Ophthalmology 1982; 89:600-4.

  12. Maureen G, Walter JS y col. Risk factors for corneal graft failure and rejection in the collaborative corneal transplantation studies. Ophthalmology 1994; 101:1536:1547.

  13. Matsuda M, Bourne W. Long-term changes in the endothelium of transplanted corneas. Ophthalmol 1985; 103:1343-1345.




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Rev Mex Oftalmol. 2006;80