López-Molina AM, Bustos-Zepeda M, Fuente-Torres MA

Language: Spanish
References: 5
Page: 219-221
PDF size: 31.12 Kb.

ABSTRACT

Objective: To compare efficacy and security of the pilocarpine versus acetylcholine for miosis in phacoemulsification.
Material and method: Prospective, comparative, blind, longitudinal and observational study. Two groups were evaluated at random considering the used miotic: group 1 (pilocarpine), group 2 (acetylcholine). All patients were evaluated with a complete ophthalmologic examination, specular microscopy before and three month after surgery and a follow up the first day, first week, first month and third month after surgery.
Results: A total of 12 patients were studied. The average cell count by specular microscopy before surgery was 2179 cells per square millimeter and 568 microns of thickness for group 1and 2202 cells per square millimeter and 545 microns for group 2. Three months after surgery the average cell count by specular microscopy was 1896 cells per square millimeter and 530 microns for group 1 and 1840 cells per square millimeter and 512 microns for group 2.
Conclusions: In our pilot study, pilocarpine was as safe and effective as intracameral acetylcholine.

REFERENCES

1. American Academy of Ophthalmology. Lens and Cataract. 1999-2000; 75-76, 91-114.

2. Wutthiphan S, Hanutsaha P, Jenchitr W. Intracameral pilocarpine in topical facoemulsification. J Med Assoc Thai 2000; 83(12):1452-7.

3. Roberts CW. Intraocular miotics and postoperative inflammation. J Cataract Refract Surg 1993; 19(6):731-4.

4. Cavanagh HD, El-Agha MS, Petroll WM, Jester JV. Specular microscopy, confocal microscopy, and ultrasound biomicroscopy: diagnostic tools of the past quarter century. Cornea 2000; 19(5):712-22.

5. Nuyts RM, Boot N, van Bets JA, Edelhauser HF, Breebaart AC. Long-term changes in human corneal endothelium following toxic endothelial cell destruction: a specular microscopy and fluorophotometric study. Br J Opththalmol 1996; 80(1):15-20.