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2008, Number 2

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Rev Med Hosp Gen Mex 2008; 71 (2)

Use of autologus serum in ocular surface pathology

Salas-Cervantes MR, Vázquez-Maya L, Hernández-Mendoza L, Palmeros-Morgado G
Full text How to cite this article

Language: Spanish
References: 23
Page: 71-76
PDF size: 142.37 Kb.


Key words:

Autologous serum, epithelial defect, ocular surface, dry eye.

ABSTRACT

The use of autologus serum in the ophthalmology field has been utilized successfully by several authors, such as a substitute of eye tear in severe dry eye problem or in persistent epithelial defects of the ocular surface. Objective: To observe the effects of autologus serum, such as a coadjuvant treatment, in patients with ocular surface pathology do not respond with traditional treatment. Material and methods: Prospective, longitudinal, not comparative case series study is performed in patients at the external Service of Cornea Department with an epithelial defect of the ocular surface, from March to November 2007. Prior a complete ophthalmologic exploration, from periphery venous blood extraction, in ophthalmology solution, autologous serum is used. Results: 16 eyes (11 patients), 8 females (73%), 3 males (27%), 46 years of age (r = 17-68). The initial tear brake -up time (TBUT) of 2.27 seconds mean, third month mean TBUT of 5.09 seconds. At the beginning the 79.5% of dye staining fluorescein (PDSF) was positive, three months after treatment PDSF result 13.6% positive cases. All the patients refer improvement in symptomatology. Conclusions: Ophthalmology solution of autologus serum, display a great utility in the ocular surface pathology when the conventional treatment is not sufficient.


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Rev Med Hosp Gen Mex. 2008;71