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Revista Mexicana de Oftalmología

Anales de la Sociedad Mexicana de Oftalmología y Archivos de la Asociación Para Evitar la Ceguera en México
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2004, Number 1

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Rev Mex Oftalmol 2004; 78 (1)

Úlcera de Mooren: prevalencia y manifestaciones clínicas

Sandoval-Ramsey G, Ruiz-Quintero N, Hernández-Quintela E, Naranjo-Tackman R
Full text How to cite this article

Language: Spanish
References: 7
Page: 26-28
PDF size: 28.53 Kb.


Key words:

Mooren ulcer, temporal limbus, visual capacity, astigmatism against the rule, ulcerative keratitis.

ABSTRACT

Objective: To know the prevalence of Mooren ulcer and its most frequents clinical manifestations in patients of the Asociación para Evitar la Ceguera en México I.A.P.
Method: The files of all patients with diagnosis of Mooren ulcer were studied retrospectively from January 1996 to August 2002.
Results: From 257,380, first time consultation patient’s ten cases with Mooren ulcer were diagnosed. This corresponded to a periodic prevalence of 3 x 100, 000. The average age was 56.4 years and 70% were females. The most frequent location was the temporal limbus (50%).
Conjunctiva hyperaemia (70%) and corneal vascularization (70%) were the most frequent signs associated to the ulceration. The average visual acuity and capacity of the affected eyes was 20/100 and 20/40 respectively. The most common refractive defect (70%) was astigmatism against the rule. The most frequent administered treatments were lubricants 80% and topical steroids 50%.
Conclusion: The prevalence found is lower than that reported in the world literature. This pathology is more frequent in adult females. The most frequent location was the temporal limbus. The clinical signs are ulcerative keratitis, conjunctival hyperaemia, vascularization and corneal leucoma.


REFERENCES

  1. Mondino BJ. Inflamatory diseases of the peripheral cornea. Ophthalmology 1988; 95(4):463-472.

  2. Tiev KP, Borderie VM, Briant M, Ziani M, Morvant C, Baret M, Khattabi AE, Genereau T, Laroche L, Cabane J. Severe Mooren’s ulcer: Efficacy of monthly cyclophosphamide intravenous pulse treatment. Rev Med Interne 2003; 24 (2):118-122.

  3. Jiaqui C, Hanping X, Zhen W, Bing Y, Zuguo L, Longshan C, Xiangming G, Yuesheng L. Mooren´s ulcer in China: a study of clinical characteristics and treatment. Br J Ophthalmol 2000; 84:1244-1249.

  4. Young RD, Watson PG. Light and electron microscopy of corneal melting syndrome (Mooren Ulcer). Br J Ophthalmol 1982; 66(6):341-356.

  5. Foster CS. Systemic Inmunosuppressive Therapy for Progressive Bilateral Mooren´s Ulcer. Ophthalmology 1985; 92:1436-1439.

  6. Jing-cheng Z, Xiu-ying J. Inmunological Analysis and Treatment of Mooren´s Ulcer with Cyclosporin A applied Topically. Cornea; 12(6):481-488.

  7. Craig JT, Smith SI, Morgan CH, Stephenson SF, Key T y cols. HLA and Mooren´s ulceration. Br J Ophthalmol 2000; 84:72-75.




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Rev Mex Oftalmol. 2004;78