Terán PMA, Gómez CRAC, Barrera LN

Language: Spanish
References: 10
Page: 37-41
PDF size: 47.44 Kb.

ABSTRACT

Introduction:The presence of cancer associated to pregnancy is an uncommon entity in the medical literature. The later age of women in getting pregnant seems to favor a greater incidence of this association.
Objective:To identify the type of neoplasms frequently associated to pregnancy, as well as to identify the factors favoring their presence.
Setting:Third level health care hospital.
Design:Retrospective, longitudinal study, without control group.
Patients and methods:We reviewed retrospectively the clinical records of 50 women with cancer associated to pregnancy in a 10 year period (1993-2003). We excluded 14 women who had no medical follow-up and did not complete their oncological treatment. Malignancy diagnosis was confirmed through histopathology and pregnancy by determination of chronic gonadotropin and/or pelvic ultrasound. The association cancer-pregnancy was classified as synchronous when they were concomitant and metachronic if cancer diagnosis was made during the first 12 months after the end of pregnancy. We studied the following variables: age at the time of diagnosis, gestational age, obstetric follow-up, complications during pregnancy, conditions of the product at birth, and follow-up time.
Results:The most frequent neoplasms were of the cervix in 20 cases (55.5%), of the breast in 7 (19.4%), and of the ovary in 3 (8.5%). Average follow-up time was 18.9 months. Average age was 30 years; 23 women presented 24 synchronous cancers with pregnancy (66.7%), and in 12, the cancers were metachronic (33.3%). Advanced stages predominated, standing out the invasive cancer of the cervix at an early age (29 years) as compared with the pre-invasive cancer (34.5%). The mean gestational age was 37.4 weeks, being lower for the cervix cancer (24.2 weeks) and breast cancer (25.5 weeks).
Conclusion:Cervix-uterine cancer was the most frequent cancer associated with pregnancy, and the synchronous variety the most common one.

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