Flores NG, Jurado HVH, Martínez MA, Tenorio MFR

Language: Spanish
References: 10
Page: 527-532
PDF size: 134.71 Kb.

ABSTRACT

Introduction: HELLP syndrome (HS) is a pregnancy complication with hemolysis, hepatic failure and thrombocytopenia. This syndrome increase maternal, fetus and neonatal morbidity and mortality.
Objective: To compare clinical features, morbidity, mortality and hematological outcome in a group with and without HS. The variables were analyzed with t´Students, chi square, and Fisher test, p significative value was ‹ 0.05.
Results: We analyzed 60 patients in both groups, and we found differences in (HS group vs no HS); Cesarean section 96 vs 68%, gestational age 33 ± 3 vs 35 ± 3, birth weight 1819 ± 604 vs 2263 ± 797 grams, length 42 ± 5 vs 45 ± 4 cm, preterm infants 88.3% vs 55%, intraventricular hemorrhage 26.6 vs 8.3%, hypocalcaemia 26.6 vs 48.3%. In the first day of life, hematic cytology with Hto 52 ± 7 vs 49 ± 8, platelets 153,804 ± 947 vs 192,822 ± 61,070 and uncongugated bilirubin 5.2 ± 3.7 vs 3.8 ± 1.9 were observed. At 2^nd day leucocytes 8030 ± 4094 vs 18020 ± 12606 and granulocytes 4734 ± 30307 vs 9324 ± 9776 were found. No differences was found in, maternal age, intrauterine growth restriction, gender, respiratory distress syndrome, asphyxia, sepsis and hepatic enzymes, morbidity 83.3 vs 86.6% (p = 0.79), and mortality 5 vs 1.6% (p = 0.61).
Conclusions: HS is an important cause of premature delivery. The neonatal morbidity is typical of preterm infants, intraventricular hemorrhage was more frequent. Mortality was not different.

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