Olín NJA, Corpus PMA

Language: Spanish
References: 18
Page: 17-23
PDF size: 871.30 Kb.

ABSTRACT

Multiple osteochondromatosis is a skeletal displasia inherited in an autosomical dominant manner "de novo" or mutation. It produces developmental of osteocartilaginous tumours that grow simultaneously with the skeleton and respond to growth spurts, cleasing at skeletal matumty. These tumors produce disturbance of normal alignment and proportion of extremities as well as postural changes. It is more frecuently seen in males during the first and second decades of life. Treatment usually includes tumor resection, osteotomies for correction of alignment, management of bone length discrepancy and observation because of a low tendency to malignization.
We describe the experience of our institute in these cases and the results of treatment.
Must patients were seen during adolescence except one and in 3 of them malignization changes were seen. Indication for surgical treatment were: pain deformity, functional, and weight bearing problems, which frecuency and carachteristics were described, and malignization.
All patients improved in some way and have been followed to the closure of the study with no evidence of recurrence in the cases with malignant transformation.

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