2004, Number 3
Rev Med Inst Mex Seguro Soc 2004; 42 (3)
Prevalence of Helicobacter pylori among Patients Infected with HIV
Urdez HE, Reglín NH, Escamilla AE, Antonio MM, León JEA, Piña VG, Hernández GMC, Terrazas EJJ
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Objective: our objective was to know prevalence of Helicobacter pylori infection among adults with HIV/AIDS.
Material and methods: during a 6-month period, patients with HIV/AIDS who had the following criteria were included in the study: 16 years of age; no therapy with antibiotic regimen or bismuth compounds during the previous 4 weeks, and written informed consent for endoscopy. Information regarding use of tap water and/or outdoor food, sexual behavior, history of both antiacid medication and gastrointestinal symptoms, reason for hospital visit, and CD4+
T cell count was compiled. Gastric (from both antrum and corpus) and duodenal biopsies were gathered to perform H. pylori culture.
Results: forty-nine patients were studied: males predominated (87 %); their mean age was 36 ± 10 years. Although the majority of study participants consumed outdoor food (75 %) and tap water (69 %), only 24 % accepted oroanal exposure; 37 individuals (76 %) visited the hospital for current symptoms that included mainly diarrhea and fever. Seventy seven percent showed 200 CD4+ T-cells/mL, while H. pylori grew from at least one sample of 24 (48.9%) individuals.
Conclusions: high rate of H. pylori infection was found among patients with HIV/AIDS, although the majority of patients had advanced immuno-suppression.
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