This journal only 2009, Number 1 Cir Gen 2009; 31 (1) Abdominal sepsis due to necrosis and gastric perforation caused by Candida spp. A propos of a case Rodea RH, López RSC, Aristi UG, Athié GC, Pérez TE Full text How to cite this article Language: Spanish References: 27 Page: 56-61 PDF size: 294.97 Kb. Key words: Candida spp, candidiasis, secondary peritonitis, gastric perforation. ABSTRACT Objective: To report a case of extensive gastric necrosis and perforation secondary to Candida spp. infection. Setting: General Hospital of Mexico (Third level health care hospital). Design: Presentation of a case. Description of the case: Man, 51 year-old, with a 5-day history of illness characterized by rejecting food and abdominal distension, who was admitted presenting acute abdomen, dehydration, and arterial hypotension; leukocytosis and pneumoperitoneum, as relevant signs. He was subjected to exploratory laparotomy, which revealed generalized peritonitis secondary to necrosis and perforation of the gastric fundus. Treatment to control the septic focus consisted of total gastrectomy with Roux–en-Y esophagus-jejunum anastomosis, lavage and drainage of the abdominal cavity, and re-operation to repair the partial dehiscence of the esophagus-jejunum anastomosis. The pathology report led to the diagnosis of chronic ulcerated acute gastritis with perforation due to Candida spp. infection and secondary ischemic pangastritis. During follow-up, esophageal candidiasis recurred that responded to medical treatment. Conclusions: Primary gastric lesions associated to Candida spp. invasion consist of ulcers and gastritis; gastric perforation is very rare and implies secondary peritonitis and potentially secondary sepsis, which are hard to eradicate if not suspected and the presence of Candida spp. is not treated. 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