Gaceta Médica de México

Contents by Year, Volume and Issue

Table of Contents

General Information

Instructions for Authors

Message to Editor

Editorial Board

>Journals >Gaceta Médica de México >Year 2008, Issue 6

Alvarado-Esquivel C, Sifuentes-Álvarez A, Pérez-Ochoa JF, García-Corral N, Rodríguez-Briones A, González-Castañeda JL, Alonso-Muñoz CMT, Bracho-Huemoeller A
Serorreactividad al antígeno de superficie del virus de la hepatitis B en diversos grupos de población de la ciudad de Durango, México.
Gac Med Mex 2008; 144 (6)

Language: Español
References: 17
Page: 481-484
PDF: 38.97 Kb.

Full text


Objective: To determine the seroprevalence of hepatitis B surface antigen (HBsAg) in several groups of populations in Durango City, Mexico. Methods: An observational and comparative study was conducted in 6 groups of population in a total of 775 persons in Durango City, Mexico. The groups studied were 141 registered female sex workers, 100 medical students, 150 blood donors, 104 persons applying for medical certificates, 100 pregnant women, and 180 drug addicts. Serum samples of participants were analyzed for HBsAg by an immunoassay. HBsAg confirmation was performed by neutralization assay. Results: Out of the 775 participants, 13 (1.7%) were positive by the immunoassay, and only 1 (0.1%) resulted positive by the confirmatory assay. This positive case was a drug addict and had a history of surgery and national and international trips. Conclusions: The seroprevalence of HBsAg in several groups of population in Durango City is low; the seroprevalence is comparable to or lower than those informed in other Mexican cities. It is strongly recommended to perform the HBsAg confirmation test due to low specificity of the immunoassay.

Key words: Hepatitis B virus, hepatitis.


  1. Tran TT, Martin P. Hepatitis B: Epidemiology and natural history. Clin Liver Dis 2004;8:255-266.

  2. Pol S. Epidemiology and natural history of hepatitis B. Rev Prat 2005;55:599- 606.

  3. Rawls RA, Vega KJ. Viral hepatitis in minority America. J Clin Gastroenterol 2005;39:144-151.

  4. Méndez-Sánchez N, Aguilar-Ramírez JR, Reyes A, Dehesa M, Juárez A, Castañeda B, et al. Etiology of liver cirrhosis in Mexico. Ann Hepatol 2004;3:30-33.

  5. Custer B, Sullivan SD, Hazlet TK, Iloeje U, Veenstra DL, Kowdley KV. Global epidemiology of hepatitis B virus. J Clin Gastroenterol 2004;38 (Suppl): S158-S168.

  6. Ranger-Rogez S, Denis F. Hepatitis B mother-to-child transmission. Expert Rev Anti Infect Ther 2004;2:133-145.

  7. Tang S, Lai KN. Chronic viral hepatitis in hemodialysis patients. Hemodial Int 2005;9:169-179.

  8. Tanaka J. Hepatitis B epidemiology in Latin America. Vaccine 2000;18(Suppl 1): S17-S19.

  9. Maddrey WC. Hepatitis B: An important public health issue. J Med Virol 2000;61:362-366.

  10. García-Montalvo BM. Seropositivity of HIV, HBV, HCV and Treponema pallidum in blood donors in southeast Mexico. Rev Invest Clin 2006;58:567-572.

  11. Vázquez-Martínez JL, Coreño-Juárez MO, Montaño-Estrada LF, Attlan M, Gómez-Dantés H. Seroprevalence of hepatitis B in pregnant women in Mexico. Salud Publica Mex 2003;45:165-170.

  12. Juárez-Figueroa L, Uribe-Salas F, Conde-González C, Hernández-Ávila M, Olamendi-Portugal M, Uribe-Zúñiga P, et al. Low prevalence of hepatitis B markers among Mexican female sex workers. Sex Transm Infect 1998;74:448- 450.

  13. Flores-Castañeda MS, García-Méndez BL, Tijerina-Menchaca R. HCV and HBV seropositivity in university students of the State of Nuevo León, México. Rev Gastroenterol Mex 1996;61:327-331.

  14. Alvarado-Esquivel C, Arellano-Santos CV, Salazar-Arana JL, Mercado- Suárez MF. Prevalence of hepatitis B virus infection in patients suffering from acute and chronic liver disease in three public hospitals in Durango, Mexico. Gac Med Mex 2006;142:447-450.

  15. Alvarado-Esquivel C, Sablon E, Martínez-García S, Estrada-Martínez S. Hepatitis virus and HIV infections in inmates of a state correctional facility in Mexico. Epidemiol Infect 2005;4:679-685.

  16. Alvarado-Esquivel C, Arreola-Valenzuela MA, Mercado-Suárez MF, Espinoza- Andrade F. Hepatitis B virus infection among inpatients of a psychiatric hospital of Mexico. Clin Pract Epidemol Ment Health 2005;1:10.

  17. Lau DT, Hewlett AT. Screening for hepatitis A and B antibodies in patients with chronic liver disease. Am J Med 2005;118 (Suppl 10A):28S-33S.

>Journals >Gaceta Médica de México >Year 2008, Issue 6

· Journal Index 
· Links 

Copyright 2019